mecA-positive methicillin-sensitive Staphylococcus aureus clinical isolates in Zenica-Doboj Canton, Bosnia and Herzegovina

F. Kamberovic, A. Ibrahimagic, S. Uzunovic, A. Budimir, M.I.A. Rijnders, E.E. Stobberingh

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Forty-four mecA-positive and eight mecA-negative Staphylococcus aureus isolates confirmed by PCR were further tested by disc-diffusion (DD) oxacillin and cefoxitin, oxacillin Epsilon (E)-test, and oxacillin and cefoxitin minimal inhibitory concentration (MIC) Strip methicillin-resistant phenotype in S. aureus (MRSA) tests. Among 44 mecA-positive S. aureus isolates, two (4.5%) were detected as MRSA by DD-oxacillin, 17 (38.6%) by DD-cefoxitin test, and seven (15.9%) by the E-test. In the cefoxitin MIC Strip MRSA test, 19 (43.2%) isolates were resistant. In the oxacillin MIC Strip MRSA test, 18 (40.9%) isolates were resistant and 26 (59.1%) were sensitive, i. e. oxacillin-sensitive MRSA (OS-MRSA) (MIC range 0.25
Original languageEnglish
Pages (from-to)330-336
JournalJournal of Chemotherapy
Volume27
Issue number6
DOIs
Publication statusPublished - 1 Jan 2015

Cite this

Kamberovic, F., Ibrahimagic, A., Uzunovic, S., Budimir, A., Rijnders, M. I. A., & Stobberingh, E. E. (2015). mecA-positive methicillin-sensitive Staphylococcus aureus clinical isolates in Zenica-Doboj Canton, Bosnia and Herzegovina. Journal of Chemotherapy, 27(6), 330-336. https://doi.org/10.1179/1973947814Y.0000000207