Mass spectrometry-based imaging

Martina Marchetti-Deschmann; Berta Cillero-Pastor; Benjamin Balluff

doi:10.1088/978-0-7503-3059-6ch43

Mass spectrometry-based imaging

Martina Marchetti-Deschmann
, Berta Cillero-Pastor
, Benjamin Balluff

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

6 Downloads (Pure)

Abstract

Mass spectrometry imaging (MSI) is a powerful imaging technique for visualizing the spatial distribution of chemical components in samples, from inorganic and organic materials to biological tissues and single cells. Contrary to other imaging techniques such as immunohistochemical imaging, chemical staining, and fluorescence microscopy, MSI is a label-free technique and enables monitoring thousands of compounds in a single experiment. Owing to its unique characteristics, especially the non-targeted detection, high chemical specificity, and high accuracy for structural elucidation, MSI has been rapidly and continuously developed to meet the expectations and needs of various research areas.

Original language	English
Title of host publication	Imaging Modalities for Biological and Preclinical Research A Compendium Volume 1 Part I Ex Vivo Biological Imaging
Editors	Andreas Walter, Julia G. Mannheim, Carmel J. Caruana
Publisher	Institute of Physics Publishing
Pages	I.9.g-1-I.9.g-10
Volume	1
ISBN (Electronic)	9780750342032
ISBN (Print)	9780750330572
DOIs	https://doi.org/10.1088/978-0-7503-3059-6ch43
Publication status	Published - 1 Jan 2021

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Marchetti-Deschmann, M., Cillero-Pastor, B., & Balluff, B. (2021). Mass spectrometry-based imaging. In A. Walter, J. G. Mannheim, & C. J. Caruana (Eds.), Imaging Modalities for Biological and Preclinical Research A Compendium Volume 1 Part I Ex Vivo Biological Imaging (Vol. 1, pp. I.9.g-1-I.9.g-10). Institute of Physics Publishing. https://doi.org/10.1088/978-0-7503-3059-6ch43

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Mass spectrometry-based imaging. / Marchetti-Deschmann, Martina; Cillero-Pastor, Berta ; Balluff, Benjamin.
Imaging Modalities for Biological and Preclinical Research A Compendium Volume 1 Part I Ex Vivo Biological Imaging. ed. / Andreas Walter; Julia G. Mannheim; Carmel J. Caruana. Vol. 1 Institute of Physics Publishing, 2021. p. I.9.g-1-I.9.g-10.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

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AB - Mass spectrometry imaging (MSI) is a powerful imaging technique for visualizing the spatial distribution of chemical components in samples, from inorganic and organic materials to biological tissues and single cells. Contrary to other imaging techniques such as immunohistochemical imaging, chemical staining, and fluorescence microscopy, MSI is a label-free technique and enables monitoring thousands of compounds in a single experiment. Owing to its unique characteristics, especially the non-targeted detection, high chemical specificity, and high accuracy for structural elucidation, MSI has been rapidly and continuously developed to meet the expectations and needs of various research areas.

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Mass spectrometry-based imaging

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