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LRP5 variants may contribute to ADPKD
Wybrich R. Cnossen
, Rene H. M. te Morsche
, Alexander Hoischen
, Christian Gilissen
, Hanka Venselaar
, Soufi Mehdi
, Carsten Bergmann
, Monique Losekoot
, Martijn H. Breuning
, Dorien J. M. Peters
, Joris A. Veltman
, Joost P. H. Drenth
*
*
Corresponding author for this work
Genetica & Celbiologie
GROW - Research Institute for Oncology and Reproduction
GROW - Reproductive and Perinatal Medicine
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INIS
diseases
100%
receptors
100%
kidneys
100%
proteins
100%
lipoproteins
100%
patients
27%
liver
18%
genes
18%
mutations
18%
tools
9%
density
9%
spectra
9%
genetics
9%
harbors
9%
adults
9%
signals
9%
luciferase
9%
Keyphrases
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
100%
Lipoprotein Receptor-related Protein
100%
PKD1
25%
Canonical Wnt Signaling Pathway
12%
Phenotypic Spectrum
12%
Pathophysiology
12%
Positive Family History
12%
Canonical Wnt Signaling
12%
Low-density Lipoprotein Receptor-related Protein 5 (LRP5)
12%
Proband
12%
Disease-related Proteins
12%
Protein Function
12%
Adult-onset
12%
Signaling Activation
12%
PKD2
12%
Polycystic Liver Disease
12%
In Silico Tools
12%
Hepatic Cystogenesis
12%
Polycystic Kidney Disease
12%
Unlinked
12%
Luciferase Activity Assay
12%
Medicine and Dentistry
Polycystic Kidney Disease
100%
Lipoprotein Receptor
100%
Wnt Signaling
22%
Pathophysiology
11%
Cell Signaling Pathway
11%
Luciferase
11%
Family History
11%
In Silico
11%
PKD1
11%
Polycystin 2
11%
Low Density Lipoprotein Receptor Related Protein 5
11%
Liver Polycystic Disease
11%
Polycystin 1
11%
Diseases
11%
Protein Function
11%
Biochemistry, Genetics and Molecular Biology
Lipoprotein Receptor-Related Protein
100%
Autosomal Dominant Polycystic Kidney
100%
Wnt Signaling Pathway
25%
PKD1
25%
Genetics
12%
Protein Function
12%
LDL Receptor
12%
Luciferase
12%
Proband
12%