Low serum vitamin K in PXE results in defective carboxylation of mineralization inhibitors similar to the GGCX mutations in the PXE-like syndrome

Olivier M. Vanakker, Ludovic Martin, Leon J. Schurgers, Daniela Quaglino, Laura Costrop, Cees Vermeer, Ivonne Pasquali-Ronchetti, Paul J. Coucke, Anne De Paepe*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

42 Citations (Web of Science)
Original languageEnglish
Pages (from-to)895-905
JournalLaboratory Investigation
Issue number6
Publication statusPublished - Jun 2010


  • elastic fibers
  • fetuin-A
  • mineralization
  • pseudoxanthoma elasticum
  • vitamin K
  • vitamin K-dependent proteins

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