Abstract
BACKGROUND AND AIMS: Epidemiological studies have indicated a negative relation between low-fat dairy consumption and the metabolic syndrome. However, evidence from intervention studies is scarce. Our aim was to investigate the effects of daily consumption of low-fat dairy products on metabolic risk parameters in overweight and obese men and women. METHODS AND RESULTS: Thirty-five healthy subjects (BMI>27kg/m(2)) consumed low-fat dairy products (500mL low-fat milk and 150g low-fat yogurt) or carbohydrate-rich control products (600mL fruit juice and 3 fruit biscuits) daily for 8 weeks in random order. Compared with the control period, systolic blood pressure was decreased by 2.9mmHg (95% confidence interval (CI), -5.5 to -0.3mmHg; P=0.027), while the difference in diastolic blood pressure did not reach statistical significance (95% CI, -3.4 to 0.3mmHg; P=0.090). Low-fat dairy consumption decreased HDL-cholesterol concentrations by 0.04mmol/L (95% CI, -0.07 to -0.01mmol/L; P=0.021) and apo A-1 concentrations by 0.04g/L (95% CI, -0.07 to -0.01g/L; P=0.016) compared with control. Serum total cholesterol, LDL-cholesterol, apo B, triacylglycerols, non-esterified fatty acids, glucose, insulin, C-reactive protein and plasminogen activator inhibitor-1 were unchanged. CONCLUSION: We conclude that in overweight and obese subjects, daily intake of low-fat dairy products for 8 weeks decreased systolic blood pressure, but did not improve other metabolic risk factors related to the metabolic syndrome.
Original language | English |
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Pages (from-to) | 355-361 |
Number of pages | 7 |
Journal | Nutrition Metabolism and Cardiovascular Diseases |
Volume | 21 |
Issue number | 5 |
DOIs | |
Publication status | Published - May 2011 |
Keywords
- Low-fat dairy
- Blood pressure
- Lipoproteins
- Overweight
- MAGNETIC-RESONANCE-SPECTROSCOPY
- SERUM-LIPIDS
- CALCIUM SUPPLEMENTATION
- INSULIN SENSITIVITY
- MONOUNSATURATED FAT
- CARBOHYDRATE INTAKE
- CONTROLLED-TRIALS
- DIETARY CALCIUM
- WEIGHT-LOSS
- PRODUCTS