Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects

Freddy Djiepmo; Bálint Tamaskovics; Edwin Bölke; Matthias Peiper; Jan Haussmann; Judith Neuwahl; Danny Jazmati; Kitti Maas; Livia Schmidt; Roman Gelzhäuser; Christoph Schleich; Stefanie Corradini; Klaus Orth; Martijn van Griensven; Amir Rezazadeh; Kimia Karimi; Wilfried Budach; Christiane Matuschek

doi:10.1186/s40001-022-00642-x

Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects

Freddy Djiepmo, Bálint Tamaskovics, Edwin Bölke^*, Matthias Peiper, Jan Haussmann, Judith Neuwahl, Danny Jazmati, Kitti Maas, Livia Schmidt, Roman Gelzhäuser, Christoph Schleich, Stefanie Corradini, Klaus Orth, Martijn van Griensven, Amir Rezazadeh, Kimia Karimi, Wilfried Budach, Christiane Matuschek

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

AIM: Plantar enthesophyte is a common degenerative disorder. Surgical and medical treatment options are associated with either poor outcome or high percentage of relapse. Observations have indicated a beneficial effect of radiation therapy. We therefore wanted to evaluate pain reduction using orthovolt or cobalt-based radiation treatment for painful plantar enthesophyte and determine long-term response as well as prognostic parameters in this condition.

METHODS: We identified a total of 102 consecutive patients treated for a total of 117 symptomatic heel spurs. 59 patients were treated with cobalt radiation, 31 patients with orthovolt therapy and 12 patients with both radiation systems. Primary outcome measure was pain reduction being scored using the modified Rowe Score prior therapy, at the end of each treatment series as well as after 6 weeks. Secondary outcome measure was long-term outcome, evaluated in patients with a follow-up period of longer than 3 years.

RESULTS: Before radiation therapy, 61 patients (60.4%) had a score of 0, significant strong pain. At the time of completion of radiation treatment, 3 patients (2.7%) were pain-free (score of 30), whereas 8 patients (7.9%) had still severe pain (score 0). 6 weeks after radiation therapy, 33 patients (32.7%) were pain-free and 8 patients (7.9%) had severe pain (score 0), while at the time data of collection, 74 patients (73%) were free of pain and 1 patient (1%) had strong pain (score 0). Duration of pain before the start of radiation treatment was a significant prognostic factor (p = 0.012) for response to treatment.

CONCLUSION: Radiotherapy of painful plantar enthesophyte is a highly effective therapy with little side effects providing long-term therapeutic response. The only significant prognostic parameter for response to treatment is the duration of pre-radiation therapy pain. Early integration of radiation therapy in the treatment seems to result in superior pain reduction.

Original language	English
Article number	28
Number of pages	11
Journal	European Journal of Medical Research
Volume	27
Issue number	1
DOIs	https://doi.org/10.1186/s40001-022-00642-x
Publication status	Published - 23 Feb 2022

Keywords

Plantar enthesophyte
Heel spur
Radiation therapy
Benign disease
Pain
Photon therapy
Electrons
SHOCK-WAVE THERAPY
HEEL SPUR
FASCIITIS
RADIOTHERAPY
MULTICENTER
PATTERNS

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Cite this

Djiepmo, F., Tamaskovics, B., Bölke, E., Peiper, M., Haussmann, J., Neuwahl, J., Jazmati, D., Maas, K., Schmidt, L., Gelzhäuser, R., Schleich, C., Corradini, S., Orth, K., van Griensven, M., Rezazadeh, A., Karimi, K., Budach, W., & Matuschek, C. (2022). Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects. European Journal of Medical Research, 27(1), Article 28. https://doi.org/10.1186/s40001-022-00642-x

@article{4f4aa5bab97241b6ba7d51fa80726c70,

title = "Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects",

abstract = "AIM: Plantar enthesophyte is a common degenerative disorder. Surgical and medical treatment options are associated with either poor outcome or high percentage of relapse. Observations have indicated a beneficial effect of radiation therapy. We therefore wanted to evaluate pain reduction using orthovolt or cobalt-based radiation treatment for painful plantar enthesophyte and determine long-term response as well as prognostic parameters in this condition.METHODS: We identified a total of 102 consecutive patients treated for a total of 117 symptomatic heel spurs. 59 patients were treated with cobalt radiation, 31 patients with orthovolt therapy and 12 patients with both radiation systems. Primary outcome measure was pain reduction being scored using the modified Rowe Score prior therapy, at the end of each treatment series as well as after 6 weeks. Secondary outcome measure was long-term outcome, evaluated in patients with a follow-up period of longer than 3 years.RESULTS: Before radiation therapy, 61 patients (60.4%) had a score of 0, significant strong pain. At the time of completion of radiation treatment, 3 patients (2.7%) were pain-free (score of 30), whereas 8 patients (7.9%) had still severe pain (score 0). 6 weeks after radiation therapy, 33 patients (32.7%) were pain-free and 8 patients (7.9%) had severe pain (score 0), while at the time data of collection, 74 patients (73%) were free of pain and 1 patient (1%) had strong pain (score 0). Duration of pain before the start of radiation treatment was a significant prognostic factor (p = 0.012) for response to treatment.CONCLUSION: Radiotherapy of painful plantar enthesophyte is a highly effective therapy with little side effects providing long-term therapeutic response. The only significant prognostic parameter for response to treatment is the duration of pre-radiation therapy pain. Early integration of radiation therapy in the treatment seems to result in superior pain reduction.",

keywords = "Plantar enthesophyte, Heel spur, Radiation therapy, Benign disease, Pain, Photon therapy, Electrons, SHOCK-WAVE THERAPY, HEEL SPUR, FASCIITIS, RADIOTHERAPY, MULTICENTER, PATTERNS",

author = "Freddy Djiepmo and B{\'a}lint Tamaskovics and Edwin B{\"o}lke and Matthias Peiper and Jan Haussmann and Judith Neuwahl and Danny Jazmati and Kitti Maas and Livia Schmidt and Roman Gelzh{\"a}user and Christoph Schleich and Stefanie Corradini and Klaus Orth and {van Griensven}, Martijn and Amir Rezazadeh and Kimia Karimi and Wilfried Budach and Christiane Matuschek",

note = "{\textcopyright} 2022. The Author(s).",

year = "2022",

month = feb,

day = "23",

doi = "10.1186/s40001-022-00642-x",

language = "English",

volume = "27",

journal = "European Journal of Medical Research",

issn = "0949-2321",

publisher = "BioMed Central",

number = "1",

}

Djiepmo, F, Tamaskovics, B, Bölke, E, Peiper, M, Haussmann, J, Neuwahl, J, Jazmati, D, Maas, K, Schmidt, L, Gelzhäuser, R, Schleich, C, Corradini, S, Orth, K, van Griensven, M, Rezazadeh, A, Karimi, K, Budach, W & Matuschek, C 2022, 'Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects', European Journal of Medical Research, vol. 27, no. 1, 28. https://doi.org/10.1186/s40001-022-00642-x

TY - JOUR

T1 - Low-dose radiation treatment for painful plantar enthesophyte

T2 - a highly effective therapy with little side effects

AU - Djiepmo, Freddy

AU - Tamaskovics, Bálint

AU - Bölke, Edwin

AU - Peiper, Matthias

AU - Haussmann, Jan

AU - Neuwahl, Judith

AU - Jazmati, Danny

AU - Maas, Kitti

AU - Schmidt, Livia

AU - Gelzhäuser, Roman

AU - Schleich, Christoph

AU - Corradini, Stefanie

AU - Orth, Klaus

AU - van Griensven, Martijn

AU - Rezazadeh, Amir

AU - Karimi, Kimia

AU - Budach, Wilfried

AU - Matuschek, Christiane

PY - 2022/2/23

Y1 - 2022/2/23

N2 - AIM: Plantar enthesophyte is a common degenerative disorder. Surgical and medical treatment options are associated with either poor outcome or high percentage of relapse. Observations have indicated a beneficial effect of radiation therapy. We therefore wanted to evaluate pain reduction using orthovolt or cobalt-based radiation treatment for painful plantar enthesophyte and determine long-term response as well as prognostic parameters in this condition.METHODS: We identified a total of 102 consecutive patients treated for a total of 117 symptomatic heel spurs. 59 patients were treated with cobalt radiation, 31 patients with orthovolt therapy and 12 patients with both radiation systems. Primary outcome measure was pain reduction being scored using the modified Rowe Score prior therapy, at the end of each treatment series as well as after 6 weeks. Secondary outcome measure was long-term outcome, evaluated in patients with a follow-up period of longer than 3 years.RESULTS: Before radiation therapy, 61 patients (60.4%) had a score of 0, significant strong pain. At the time of completion of radiation treatment, 3 patients (2.7%) were pain-free (score of 30), whereas 8 patients (7.9%) had still severe pain (score 0). 6 weeks after radiation therapy, 33 patients (32.7%) were pain-free and 8 patients (7.9%) had severe pain (score 0), while at the time data of collection, 74 patients (73%) were free of pain and 1 patient (1%) had strong pain (score 0). Duration of pain before the start of radiation treatment was a significant prognostic factor (p = 0.012) for response to treatment.CONCLUSION: Radiotherapy of painful plantar enthesophyte is a highly effective therapy with little side effects providing long-term therapeutic response. The only significant prognostic parameter for response to treatment is the duration of pre-radiation therapy pain. Early integration of radiation therapy in the treatment seems to result in superior pain reduction.

AB - AIM: Plantar enthesophyte is a common degenerative disorder. Surgical and medical treatment options are associated with either poor outcome or high percentage of relapse. Observations have indicated a beneficial effect of radiation therapy. We therefore wanted to evaluate pain reduction using orthovolt or cobalt-based radiation treatment for painful plantar enthesophyte and determine long-term response as well as prognostic parameters in this condition.METHODS: We identified a total of 102 consecutive patients treated for a total of 117 symptomatic heel spurs. 59 patients were treated with cobalt radiation, 31 patients with orthovolt therapy and 12 patients with both radiation systems. Primary outcome measure was pain reduction being scored using the modified Rowe Score prior therapy, at the end of each treatment series as well as after 6 weeks. Secondary outcome measure was long-term outcome, evaluated in patients with a follow-up period of longer than 3 years.RESULTS: Before radiation therapy, 61 patients (60.4%) had a score of 0, significant strong pain. At the time of completion of radiation treatment, 3 patients (2.7%) were pain-free (score of 30), whereas 8 patients (7.9%) had still severe pain (score 0). 6 weeks after radiation therapy, 33 patients (32.7%) were pain-free and 8 patients (7.9%) had severe pain (score 0), while at the time data of collection, 74 patients (73%) were free of pain and 1 patient (1%) had strong pain (score 0). Duration of pain before the start of radiation treatment was a significant prognostic factor (p = 0.012) for response to treatment.CONCLUSION: Radiotherapy of painful plantar enthesophyte is a highly effective therapy with little side effects providing long-term therapeutic response. The only significant prognostic parameter for response to treatment is the duration of pre-radiation therapy pain. Early integration of radiation therapy in the treatment seems to result in superior pain reduction.

KW - Plantar enthesophyte

KW - Heel spur

KW - Radiation therapy

KW - Benign disease

KW - Pain

KW - Photon therapy

KW - Electrons

KW - SHOCK-WAVE THERAPY

KW - HEEL SPUR

KW - FASCIITIS

KW - RADIOTHERAPY

KW - MULTICENTER

KW - PATTERNS

U2 - 10.1186/s40001-022-00642-x

DO - 10.1186/s40001-022-00642-x

M3 - Article

C2 - 35197107

SN - 0949-2321

VL - 27

JO - European Journal of Medical Research

JF - European Journal of Medical Research

IS - 1

M1 - 28

ER -