Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke

David Stegner; Sebastian Hofmann; Michael K. Schuhmann; Peter Kraft; Alexander M. Herrmann; Sandy Popp; Marlen Hoehn; Michael Popp; Vanessa Klaus; Antonia Post; Christoph Kleinschnitz; Attila Braun; Sven G. Meuth; Klaus-Peter Lesch; Guido Stoll; Robert Kraft; Bernhard Nieswandt

doi:10.1161/STROKEAHA.119.025357

Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke

David Stegner, Sebastian Hofmann, Michael K. Schuhmann, Peter Kraft, Alexander M. Herrmann, Sandy Popp, Marlen Hoehn, Michael Popp, Vanessa Klaus, Antonia Post, Christoph Kleinschnitz, Attila Braun, Sven G. Meuth, Klaus-Peter Lesch, Guido Stoll, Robert Kraft^*, Bernhard Nieswandt^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	3238-3245
Number of pages	8
Journal	Stroke
Volume	50
Issue number	11
DOIs	https://doi.org/10.1161/STROKEAHA.119.025357
Publication status	Published - Nov 2019

Keywords

calcium
cell death
neurons
neuroprotection
reperfusion
RETICULUM CALCIUM SENSORS
MAST-CELL ACTIVATION
ENDOVASCULAR THROMBECTOMY
MOLECULAR-MECHANISMS
GLUCOSE DEPRIVATION
STORE
RELEASE
STIM2
CHANNELS
ORAI1

Access to Document

10.1161/STROKEAHA.119.025357

Cite this

Stegner, D., Hofmann, S., Schuhmann, M. K., Kraft, P., Herrmann, A. M., Popp, S., Hoehn, M., Popp, M., Klaus, V., Post, A., Kleinschnitz, C., Braun, A., Meuth, S. G., Lesch, K-P., Stoll, G., Kraft, R., & Nieswandt, B. (2019). Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke. Stroke, 50(11), 3238-3245. https://doi.org/10.1161/STROKEAHA.119.025357

Stegner, David ; Hofmann, Sebastian ; Schuhmann, Michael K. ; Kraft, Peter ; Herrmann, Alexander M. ; Popp, Sandy ; Hoehn, Marlen ; Popp, Michael ; Klaus, Vanessa ; Post, Antonia ; Kleinschnitz, Christoph ; Braun, Attila ; Meuth, Sven G. ; Lesch, Klaus-Peter ; Stoll, Guido ; Kraft, Robert ; Nieswandt, Bernhard. / Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke. In: Stroke. 2019 ; Vol. 50, No. 11. pp. 3238-3245.

@article{a4ed66e255494fc0afe5d2c661a743a8,

title = "Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke",

keywords = "calcium, cell death, neurons, neuroprotection, reperfusion, RETICULUM CALCIUM SENSORS, MAST-CELL ACTIVATION, ENDOVASCULAR THROMBECTOMY, MOLECULAR-MECHANISMS, GLUCOSE DEPRIVATION, STORE, RELEASE, STIM2, CHANNELS, ORAI1",

author = "David Stegner and Sebastian Hofmann and Schuhmann, {Michael K.} and Peter Kraft and Herrmann, {Alexander M.} and Sandy Popp and Marlen Hoehn and Michael Popp and Vanessa Klaus and Antonia Post and Christoph Kleinschnitz and Attila Braun and Meuth, {Sven G.} and Klaus-Peter Lesch and Guido Stoll and Robert Kraft and Bernhard Nieswandt",

year = "2019",

month = nov,

doi = "10.1161/STROKEAHA.119.025357",

language = "English",

volume = "50",

pages = "3238--3245",

journal = "Stroke",

issn = "0039-2499",

publisher = "LIPPINCOTT WILLIAMS & WILKINS",

number = "11",

}

Stegner, D, Hofmann, S, Schuhmann, MK, Kraft, P, Herrmann, AM, Popp, S, Hoehn, M, Popp, M, Klaus, V, Post, A, Kleinschnitz, C, Braun, A, Meuth, SG, Lesch, K-P, Stoll, G, Kraft, R & Nieswandt, B 2019, 'Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke', Stroke, vol. 50, no. 11, pp. 3238-3245. https://doi.org/10.1161/STROKEAHA.119.025357

Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke. / Stegner, David; Hofmann, Sebastian; Schuhmann, Michael K.; Kraft, Peter; Herrmann, Alexander M.; Popp, Sandy; Hoehn, Marlen; Popp, Michael; Klaus, Vanessa; Post, Antonia; Kleinschnitz, Christoph; Braun, Attila; Meuth, Sven G.; Lesch, Klaus-Peter; Stoll, Guido; Kraft, Robert; Nieswandt, Bernhard.

In: Stroke, Vol. 50, No. 11, 11.2019, p. 3238-3245.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke

AU - Stegner, David

AU - Hofmann, Sebastian

AU - Schuhmann, Michael K.

AU - Kraft, Peter

AU - Herrmann, Alexander M.

AU - Popp, Sandy

AU - Hoehn, Marlen

AU - Popp, Michael

AU - Klaus, Vanessa

AU - Post, Antonia

AU - Kleinschnitz, Christoph

AU - Braun, Attila

AU - Meuth, Sven G.

AU - Lesch, Klaus-Peter

AU - Stoll, Guido

AU - Kraft, Robert

AU - Nieswandt, Bernhard

PY - 2019/11

Y1 - 2019/11

KW - calcium

KW - cell death

KW - neurons

KW - neuroprotection

KW - reperfusion

KW - RETICULUM CALCIUM SENSORS

KW - MAST-CELL ACTIVATION

KW - ENDOVASCULAR THROMBECTOMY

KW - MOLECULAR-MECHANISMS

KW - GLUCOSE DEPRIVATION

KW - STORE

KW - RELEASE

KW - STIM2

KW - CHANNELS

KW - ORAI1

U2 - 10.1161/STROKEAHA.119.025357

DO - 10.1161/STROKEAHA.119.025357

M3 - Article

VL - 50

SP - 3238

EP - 3245

JO - Stroke

JF - Stroke

SN - 0039-2499

IS - 11

ER -