TY - JOUR
T1 - Long-term restoration of bowel continuity after rectal cancer resection and the influence of surgical technique
T2 - A nationwide cross-sectional study
AU - Hazen, Sanne-Marije J. A.
AU - van Geffen, Eline G. M.
AU - Sluckin, Tania C.
AU - Beets, Geerard L.
AU - Belgers, Henricus J.
AU - Borstlap, Wernard A. A.
AU - Consten, Esther C. J.
AU - Dekker, Jan-Willem T.
AU - Hompes, Roel
AU - Tuynman, Jurriaan B.
AU - van Westreenen, Henderik L.
AU - de Wilt, Johannes H. W.
AU - Tanis, Pieter J.
AU - Kusters, Miranda
AU - Dutch Snapshot Res Grp
PY - 2024/6
Y1 - 2024/6
N2 - AimLiterature on nationwide long-term permanent stoma rates after rectal cancer resection in the minimally invasive era is scarce. The aim of this population-based study was to provide more insight into the permanent stoma rate with interhospital variability (IHV) depending on surgical technique, with pelvic sepsis, unplanned reinterventions and readmissions as secondary outcomes.MethodPatients who underwent open or minimally invasive resection of rectal cancer (lower border below the sigmoid take-off) in 67 Dutch centres in 2016 were included in this cross-sectional cohort study.ResultsAmong 2530 patients, 1470 underwent a restorative resection (58%), 356 a Hartmann's procedure (14%, IHV 0%-42%) and 704 an abdominoperineal resection (28%, IHV 3%-60%). Median follow-up was 51 months. The overall permanent stoma rate at last follow-up was 50% (IHV 13%-79%) and the unintentional permanent stoma rate, permanent stoma after a restorative procedure or an unplanned Hartmann's procedure, was 11% (IHV 0%-29%). A total of 2165 patients (86%) underwent a minimally invasive resection: 1760 conventional (81%), 170 transanal (8%) and 235 robot-assisted (11%). An anastomosis was created in 59%, 80% and 66%, with corresponding unintentional permanent stoma rates of 12%, 24% and 14% (p = 0.001), respectively. When corrected for age, American Society of Anesthesiologists classification, cTNM, distance to the anorectal junction and neoadjuvant (chemo)radiotherapy, the minimally invasive technique was not associated with an unintended permanent stoma (p = 0.071) after a restorative procedure.ConclusionA remarkable IHV in the permanent stoma rate after rectal cancer resection was found. No beneficial influence of transanal or robot-assisted laparoscopy on the unintentional permanent stoma rate was found, although this might be caused by the surgical learning curve. A reduction in IHV and improving preoperative counselling for decision-making for restorative procedures are required.
AB - AimLiterature on nationwide long-term permanent stoma rates after rectal cancer resection in the minimally invasive era is scarce. The aim of this population-based study was to provide more insight into the permanent stoma rate with interhospital variability (IHV) depending on surgical technique, with pelvic sepsis, unplanned reinterventions and readmissions as secondary outcomes.MethodPatients who underwent open or minimally invasive resection of rectal cancer (lower border below the sigmoid take-off) in 67 Dutch centres in 2016 were included in this cross-sectional cohort study.ResultsAmong 2530 patients, 1470 underwent a restorative resection (58%), 356 a Hartmann's procedure (14%, IHV 0%-42%) and 704 an abdominoperineal resection (28%, IHV 3%-60%). Median follow-up was 51 months. The overall permanent stoma rate at last follow-up was 50% (IHV 13%-79%) and the unintentional permanent stoma rate, permanent stoma after a restorative procedure or an unplanned Hartmann's procedure, was 11% (IHV 0%-29%). A total of 2165 patients (86%) underwent a minimally invasive resection: 1760 conventional (81%), 170 transanal (8%) and 235 robot-assisted (11%). An anastomosis was created in 59%, 80% and 66%, with corresponding unintentional permanent stoma rates of 12%, 24% and 14% (p = 0.001), respectively. When corrected for age, American Society of Anesthesiologists classification, cTNM, distance to the anorectal junction and neoadjuvant (chemo)radiotherapy, the minimally invasive technique was not associated with an unintended permanent stoma (p = 0.071) after a restorative procedure.ConclusionA remarkable IHV in the permanent stoma rate after rectal cancer resection was found. No beneficial influence of transanal or robot-assisted laparoscopy on the unintentional permanent stoma rate was found, although this might be caused by the surgical learning curve. A reduction in IHV and improving preoperative counselling for decision-making for restorative procedures are required.
KW - permanent stoma
KW - rectal cancer
KW - robot-assisted laparoscopy
KW - total mesorectal excision
KW - transanal total mesorectal excision
KW - PREOPERATIVE RADIOTHERAPY
KW - SURGERY
KW - RISK
KW - MULTICENTER
KW - SURVIVAL
KW - TRIAL
U2 - 10.1111/codi.17015
DO - 10.1111/codi.17015
M3 - Article
SN - 1462-8910
VL - 26
SP - 1153
EP - 1165
JO - Colorectal Disease
JF - Colorectal Disease
IS - 6
ER -