Long-term intermittent versus short continuous heart rhythm monitoring for the detection of atrial fibrillation recurrences after catheter ablation

Astrid N. L. Hermans, Monika Gawalko, Nikki A. H. A. Pluymaekers, Trang Dinh, Bob Weijs, Manouk J. W. van Mourik, Bianca Vorstermans, Dennis W. den Uijl, Ludo Opsteyn, Hilco Snippe, Kevin Vernooy, Harry J. G. M. Crijns, Dominik Linz, Justin G. L. M. Luermans*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Web of Science)


Background: The utility of long-term intermittent heart rhythm monitoring after atrial fibrillation (AF) ablation remains undear. Therefore, we compared the efficacy and usability of long-term intermittent (AliveCor Kardia (R) (ACK)) versus short continuous (Hotter) heart rhythm monitoring for the detection of AF recurrences after AF ablation and evaluated ACK accuracy to detect AF.

Methods: Patients were provided with Hotter (for >= 24 h) simultaneously with an ACK (4 weeks) used three times a day and in case of symptoms. The primary endpoint was the difference in proportion of patients diagnosed with recurrent AF by ACK as compared to Holier monitoring. Secondary endpoints were the usability (System Usability Scale and a four-item questionnaire) of ACK and Holler monitoring; and the accuracy of the ACK algorithm for AF detection.

Results: Out of 126 post-ablation patients, 115 (91.3%; 35 females, median age 64.0 [58.0-68.0] years) transmitted overall 7838 ACK ECG recordings. ACK and Holler monitoring detected 29 (252%) and 17 (14.8%) patients with AF recurrences, respectively (p < 0.001). More than 2 weeks of ACK monitoring did not have additional diagnostic yield for detection of AF recurrences. Patients graded ACK higher than Hotter monitoring and found ACK more convenient in daily usage than Holler (p < 0.001). Sensitivity and specificity of ACK for AF detection were 95.3% and 97.5%, respectively.

Conclusions: Long-term intermittent monitoring by ACK more effectively detects AF recurrences after AF ablation and has a higher patients' usability than short continuous Holter monitoring. ACK showed a high accuracy to detect AF. (C) 2021 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)105-112
Number of pages8
JournalInternational Journal of Cardiology
Publication statusPublished - 15 Apr 2021


  • AliveCor
  • Atrial fibrillation
  • Holter
  • Telemonitoring
  • e-health
  • m-health

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