TY - JOUR
T1 - Long-Term Effects of Radioiodine Treatment on Female Fertility in Survivors of Childhood Differentiated Thyroid Carcinoma
AU - Nies, Marloes
AU - Cantineau, Astrid E. P.
AU - Arts, Eus G. J. M.
AU - van den Berg, Marleen H.
AU - van Leeuwen, Flora E.
AU - Kobold, Anneke C. Muller
AU - Hesselink, Marielle S. Klein
AU - Burgerhof, Johannes G. M.
AU - Brouwers, Adrienne H.
AU - van Dam, Eveline W. C. M.
AU - Havekes, Bas
AU - van den Heuvel-Eibrink, Marry M.
AU - Corssmit, Eleonora P. M.
AU - Kremer, Leontien C. M.
AU - Netea-Maier, Romana T.
AU - van der Pal, Helena J. H.
AU - Peeters, Robin P.
AU - Plukker, John T. M.
AU - Ronckers, Cecile M.
AU - van Santen, Hanneke M.
AU - van der Horst-Schrivers, Anouk N. A.
AU - Tissing, Wim J. E.
AU - Bocca, Gianni
AU - van Dulmen-den Broeder, Eline
AU - Links, Thera P.
N1 - Funding Information:
This work was supported by the Stichting Kinderen Kankervrij (Foundation Children Cancer-free, The Netherlands, project no. 81). C.M.R. is supported by the Dutch Cancer Society.
Publisher Copyright:
© Copyright 2020, Mary Ann Liebert, Inc., publishers 2020.
PY - 2020/8/1
Y1 - 2020/8/1
N2 - Background: Differentiated thyroid carcinoma (DTC) during childhood is a rare disease. Its excellent survival rate requires a focus on possible long-term adverse effects. This study aimed to evaluate fertility in female survivors of childhood DTC by assessing various reproductive characteristics combined with anti-Mullerian hormone (AMH) levels (a marker of ovarian reserve).Methods: Female survivors of childhood DTC, diagnosed atConclusions: Female survivors of DTC who received I-131 treatment during childhood do not appear to have major abnormalities in reproductive characteristics nor in predictors of ovarian failure.
AB - Background: Differentiated thyroid carcinoma (DTC) during childhood is a rare disease. Its excellent survival rate requires a focus on possible long-term adverse effects. This study aimed to evaluate fertility in female survivors of childhood DTC by assessing various reproductive characteristics combined with anti-Mullerian hormone (AMH) levels (a marker of ovarian reserve).Methods: Female survivors of childhood DTC, diagnosed atConclusions: Female survivors of DTC who received I-131 treatment during childhood do not appear to have major abnormalities in reproductive characteristics nor in predictors of ovarian failure.
KW - differentiated thyroid carcinoma
KW - childhood cancer
KW - adverse effects
KW - fertility
KW - radioiodine
KW - ANTI-MULLERIAN HORMONE
KW - RADIOACTIVE IODINE ABLATION
KW - OVARIAN RESERVE
KW - I-131 THERAPY
KW - ANTIMULLERIAN HORMONE
KW - CANCER
KW - PREGNANCY
KW - CHILDREN
KW - WOMEN
KW - AMH
U2 - 10.1089/thy.2019.0560
DO - 10.1089/thy.2019.0560
M3 - Article
C2 - 32079487
SN - 1050-7256
VL - 30
SP - 1169
EP - 1176
JO - Thyroid
JF - Thyroid
IS - 8
ER -