TY - JOUR
T1 - Long-Term Clinical Outcome of the Symmetry Aortic Connector System in Off-Pump Coronary Artery Bypass Grafting
AU - Verberkmoes, Niels J.
AU - Mokhles, M. Mostafa
AU - Bramer, Sander
AU - van Straten, Albert H. M.
AU - ter Woorst, Joost F.
AU - Maessen, Jos G.
AU - Berreklouw, Eric
PY - 2013/12
Y1 - 2013/12
N2 - Background Several short-term and midterm follow-up studies of the Symmetry aortic connector system showed controversial results. The objective of the present study was assessing the long-term clinical outcome of patients operated with the Symmetry device and to compare the results with hand-sewn control patients. MethodsA retrospective case-control study of 156 (46 cases, 110 controls) consecutive patients, that underwent off-pump coronary revascularization, between January 2001 and December 2004, was conducted. Study endpoints were all-cause mortality, coronary reintervention and postoperative stroke. ResultsThere was no difference in survival between cases and controls (89.1 vs. 82.4%, p=0.27) after 8 years of follow-up. No significant difference could be detected between cases and controls with respect to overall long-term coronary reintervention free survival (82.6 vs. 88.9%, p=0.41) and freedom from coronary reintervention due to proximal vein graft failure (91.3 vs. 96.3%, p=0.24). The use of Symmetry device could not be identified as independent risk-factor of coronary reintervention due to proximal vein graft failure (p=0.25). Furthermore, postoperative stroke rates were comparable between cases and controls (0.0 vs. 0.9%, p=1.00). ConclusionThis study suggests that the use of the Symmetry Bypass Connector was not associated with adverse outcome in terms of overall survival, long-term coronary reintervention free survival, freedom from reintervention due to proximal vein graft failure and postoperative stroke.
AB - Background Several short-term and midterm follow-up studies of the Symmetry aortic connector system showed controversial results. The objective of the present study was assessing the long-term clinical outcome of patients operated with the Symmetry device and to compare the results with hand-sewn control patients. MethodsA retrospective case-control study of 156 (46 cases, 110 controls) consecutive patients, that underwent off-pump coronary revascularization, between January 2001 and December 2004, was conducted. Study endpoints were all-cause mortality, coronary reintervention and postoperative stroke. ResultsThere was no difference in survival between cases and controls (89.1 vs. 82.4%, p=0.27) after 8 years of follow-up. No significant difference could be detected between cases and controls with respect to overall long-term coronary reintervention free survival (82.6 vs. 88.9%, p=0.41) and freedom from coronary reintervention due to proximal vein graft failure (91.3 vs. 96.3%, p=0.24). The use of Symmetry device could not be identified as independent risk-factor of coronary reintervention due to proximal vein graft failure (p=0.25). Furthermore, postoperative stroke rates were comparable between cases and controls (0.0 vs. 0.9%, p=1.00). ConclusionThis study suggests that the use of the Symmetry Bypass Connector was not associated with adverse outcome in terms of overall survival, long-term coronary reintervention free survival, freedom from reintervention due to proximal vein graft failure and postoperative stroke.
KW - coronary artery bypass grafts surgery CABG
KW - off-pump surgery
KW - surgical equipment (instruments sutures etc.)
KW - outcomes (includes mortality morbidity)
U2 - 10.1055/s-0032-1311539
DO - 10.1055/s-0032-1311539
M3 - Article
C2 - 22684413
SN - 0171-6425
VL - 61
SP - 669
EP - 675
JO - Thoracic and Cardiovascular Surgeon
JF - Thoracic and Cardiovascular Surgeon
IS - 8
ER -