Long-Term Ambient Residential Traffic-Related Exposures and Measurement Error-Adjusted Risk of Incident Lung Cancer in the Netherlands Cohort Study on Diet and Cancer

J.E. Hart, D. Spiegelman, R. Beelen, G. Hoek, B. Brunekreef, L.J. Schouten, P. van den Brandt

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: The International Agency for Research on Cancer (IARC) recently declared air pollution carcinogenic to humans. However, no study of air pollution and lung cancer to date has incorporated adjustment for exposure measurement error, and few have examined specific -histological subtypes. Objectives: Our aim was to assess the association of air pollution and incident lung cancer in the Netherlands Cohort Study on Diet and Cancer and the impact of measurement error on these associations. Methods: The cohort was followed from 1986 through 2003, and 3,355 incident cases were identified. Cox proportional hazards models were used to estimate hazard ratios and 95% confidence intervals, for long-term exposures to nitrogen dioxide (NO2), black smoke (BS), PM2.5 (particulate matter with diameter
Original languageEnglish
Pages (from-to)860-866
JournalEnvironmental Health Perspectives
Volume123
Issue number9
DOIs
Publication statusPublished - 1 Jan 2015

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