Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes

Ruth C. R. Meex*, Ellen E. Blaak, Luc J. C. van Loon

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1205-1217
Number of pages13
JournalObesity Reviews
Volume20
Issue number9
DOIs
Publication statusPublished - Sep 2019

Keywords

  • insulin resistance
  • interorgan crosstalk
  • muscle atrophy
  • obesity
  • HUMAN SKELETAL-MUSCLE
  • INTRAMYOCELLULAR LIPID-CONTENT
  • PROTEIN SYNTHETIC RESPONSE
  • ADIPOSE-TISSUE
  • OLDER-ADULTS
  • SARCOPENIC OBESITY
  • BODY-COMPOSITION
  • FATTY-ACID
  • MITOCHONDRIAL-FUNCTION
  • ANABOLIC RESISTANCE

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