Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes

Ruth C. R. Meex*, Ellen E. Blaak, Luc J. C. van Loon

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1205-1217
Number of pages13
JournalObesity Reviews
Volume20
Issue number9
DOIs
Publication statusPublished - Sep 2019

Keywords

  • insulin resistance
  • interorgan crosstalk
  • muscle atrophy
  • obesity
  • HUMAN SKELETAL-MUSCLE
  • INTRAMYOCELLULAR LIPID-CONTENT
  • PROTEIN SYNTHETIC RESPONSE
  • ADIPOSE-TISSUE
  • OLDER-ADULTS
  • SARCOPENIC OBESITY
  • BODY-COMPOSITION
  • FATTY-ACID
  • MITOCHONDRIAL-FUNCTION
  • ANABOLIC RESISTANCE

Cite this

@article{f0e70532ac0041f985fa459172b460c2,
title = "Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes",
keywords = "insulin resistance, interorgan crosstalk, muscle atrophy, obesity, HUMAN SKELETAL-MUSCLE, INTRAMYOCELLULAR LIPID-CONTENT, PROTEIN SYNTHETIC RESPONSE, ADIPOSE-TISSUE, OLDER-ADULTS, SARCOPENIC OBESITY, BODY-COMPOSITION, FATTY-ACID, MITOCHONDRIAL-FUNCTION, ANABOLIC RESISTANCE",
author = "Meex, {Ruth C. R.} and Blaak, {Ellen E.} and {van Loon}, {Luc J. C.}",
year = "2019",
month = "9",
doi = "10.1111/obr.12862",
language = "English",
volume = "20",
pages = "1205--1217",
journal = "Obesity Reviews",
issn = "1467-7881",
publisher = "Wiley",
number = "9",

}

TY - JOUR

T1 - Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes

AU - Meex, Ruth C. R.

AU - Blaak, Ellen E.

AU - van Loon, Luc J. C.

PY - 2019/9

Y1 - 2019/9

KW - insulin resistance

KW - interorgan crosstalk

KW - muscle atrophy

KW - obesity

KW - HUMAN SKELETAL-MUSCLE

KW - INTRAMYOCELLULAR LIPID-CONTENT

KW - PROTEIN SYNTHETIC RESPONSE

KW - ADIPOSE-TISSUE

KW - OLDER-ADULTS

KW - SARCOPENIC OBESITY

KW - BODY-COMPOSITION

KW - FATTY-ACID

KW - MITOCHONDRIAL-FUNCTION

KW - ANABOLIC RESISTANCE

U2 - 10.1111/obr.12862

DO - 10.1111/obr.12862

M3 - Article

VL - 20

SP - 1205

EP - 1217

JO - Obesity Reviews

JF - Obesity Reviews

SN - 1467-7881

IS - 9

ER -