Limiting viral infections with immunomodulating agents

G.R.-G.J.L. Gaajetaan

Research output: ThesisDoctoral ThesisInternal

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Abstract

Viral infections occur often and they can cause serious health problems. Despite the success of the current antiviral drugs and vaccines, new medication is necessary. In this dissertation, a series of experiments shows that specific drugs that can strengthen the immune system, are capable of protecting cells against viral infections. Here, particularly the substance interferon-beta turned out to play an important role. Moreover, it turned out that direct exposure of cells to interferon-beta led to long-term protection against a viral infection. These findings may be important for the future treatment of patients with an increased sensitivity to viral infections.

Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • Bruggeman, Catharina, Supervisor
  • Stassen, Frank, Advisor
Award date29 Nov 2012
Place of PublicationMaastricht
Publisher
Publication statusPublished - 1 Jan 2012

Keywords

  • viral infections
  • health problems
  • interferon-beta
  • immunity stimulation

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