LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and FHL2 genetic variation associates with human venous thrombosis

Chantal Kroone, Mariska Vos, Timo Rademakers, Marijke Kuijpers, Mark Hoogenboezem, Jaap van Buul, Johan W M Heemskerk, Wolfram Ruf, Astrid van Hylckama Vlieg, Henri H Versteeg, Marie-José Goumans, Carlie J M de Vries, Kondababu Kurakula*, INVENT Consortium

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1677-1685
Number of pages9
JournalHaematologica-the Hematology Journal
Volume105
Issue number6
Early online date29 Aug 2019
DOIs
Publication statusPublished - Jun 2020

Keywords

  • SMOOTH-MUSCLE-CELLS
  • FACTOR EXPRESSION
  • PROCOAGULANT ACTIVITY
  • ENDOTHELIAL-CELLS
  • COAGULATION
  • ACTIVATION
  • THROMBOMODULIN
  • RECEPTORS
  • INDUCTION
  • MONOCYTES

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