Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men

Andrew M. Holwerda; Kevin J. M. Paulussen; Maarten Overkamp; Joy P. B. Goessens; Irene-Fleur Kramer; Will K. W. H. Wodzig; Lex B. Verdijk; Lisette C. P. G. M. de Groot; Luc J. C. van Loon

doi:10.1152/ajpendo.00073.2019

Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men

Andrew M. Holwerda, Kevin J. M. Paulussen, Maarten Overkamp, Joy P. B. Goessens, Irene-Fleur Kramer, Will K. W. H. Wodzig, Lex B. Verdijk, Lisette C. P. G. M. de Groot, Luc J. C. van Loon^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	E473-E482
Number of pages	10
Journal	American Journal of Physiology : Endocrinology and Metabolism
Volume	317
Issue number	3
DOIs	https://doi.org/10.1152/ajpendo.00073.2019
Publication status	Published - Sep 2019

Keywords

aging
exercise
leucine
muscle protein synthesis
sarcopenia
dietary protein
ESSENTIAL AMINO-ACIDS
LABELED MILK PROTEIN
SKELETAL-MUSCLE
NEONATAL PIGS
S6K1 PHOSPHORYLATION
SIGNALING RESPONSES
SYNTHESIS RATES
WHEY-PROTEIN
ELDERLY-MEN
IN-VIVO

Access to Document

10.1152/ajpendo.00073.2019

Cite this

Holwerda, A. M., Paulussen, K. J. M., Overkamp, M., Goessens, J. P. B., Kramer, I-F., Wodzig, W. K. W. H., Verdijk, L. B., de Groot, L. C. P. G. M., & van Loon, L. J. C. (2019). Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men. American Journal of Physiology : Endocrinology and Metabolism, 317(3), E473-E482. https://doi.org/10.1152/ajpendo.00073.2019

Holwerda, Andrew M. ; Paulussen, Kevin J. M. ; Overkamp, Maarten ; Goessens, Joy P. B. ; Kramer, Irene-Fleur ; Wodzig, Will K. W. H. ; Verdijk, Lex B. ; de Groot, Lisette C. P. G. M. ; van Loon, Luc J. C. / Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men. In: American Journal of Physiology : Endocrinology and Metabolism. 2019 ; Vol. 317, No. 3. pp. E473-E482.

@article{2389dd1e4acf43149d886150c5d644d3,

title = "Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men",

keywords = "aging, exercise, leucine, muscle protein synthesis, sarcopenia, dietary protein, ESSENTIAL AMINO-ACIDS, LABELED MILK PROTEIN, SKELETAL-MUSCLE, NEONATAL PIGS, S6K1 PHOSPHORYLATION, SIGNALING RESPONSES, SYNTHESIS RATES, WHEY-PROTEIN, ELDERLY-MEN, IN-VIVO",

author = "Holwerda, {Andrew M.} and Paulussen, {Kevin J. M.} and Maarten Overkamp and Goessens, {Joy P. B.} and Irene-Fleur Kramer and Wodzig, {Will K. W. H.} and Verdijk, {Lex B.} and {de Groot}, {Lisette C. P. G. M.} and {van Loon}, {Luc J. C.}",

year = "2019",

month = sep,

doi = "10.1152/ajpendo.00073.2019",

language = "English",

volume = "317",

pages = "E473--E482",

journal = "American Journal of Physiology : Endocrinology and Metabolism",

issn = "0193-1849",

publisher = "American Physiological Society",

number = "3",

}

Holwerda, AM, Paulussen, KJM, Overkamp, M, Goessens, JPB, Kramer, I-F, Wodzig, WKWH , Verdijk, LB, de Groot, LCPGM & van Loon, LJC 2019, 'Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men', American Journal of Physiology : Endocrinology and Metabolism, vol. 317, no. 3, pp. E473-E482. https://doi.org/10.1152/ajpendo.00073.2019

Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men. / Holwerda, Andrew M.; Paulussen, Kevin J. M.; Overkamp, Maarten; Goessens, Joy P. B.; Kramer, Irene-Fleur; Wodzig, Will K. W. H.; Verdijk, Lex B.; de Groot, Lisette C. P. G. M.; van Loon, Luc J. C.

In: American Journal of Physiology : Endocrinology and Metabolism, Vol. 317, No. 3, 09.2019, p. E473-E482.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men

AU - Holwerda, Andrew M.

AU - Paulussen, Kevin J. M.

AU - Overkamp, Maarten

AU - Goessens, Joy P. B.

AU - Kramer, Irene-Fleur

AU - Wodzig, Will K. W. H.

AU - Verdijk, Lex B.

AU - de Groot, Lisette C. P. G. M.

AU - van Loon, Luc J. C.

PY - 2019/9

Y1 - 2019/9

KW - aging

KW - exercise

KW - leucine

KW - muscle protein synthesis

KW - sarcopenia

KW - dietary protein

KW - ESSENTIAL AMINO-ACIDS

KW - LABELED MILK PROTEIN

KW - SKELETAL-MUSCLE

KW - NEONATAL PIGS

KW - S6K1 PHOSPHORYLATION

KW - SIGNALING RESPONSES

KW - SYNTHESIS RATES

KW - WHEY-PROTEIN

KW - ELDERLY-MEN

KW - IN-VIVO

U2 - 10.1152/ajpendo.00073.2019

DO - 10.1152/ajpendo.00073.2019

M3 - Article

VL - 317

SP - E473-E482

JO - American Journal of Physiology : Endocrinology and Metabolism

JF - American Journal of Physiology : Endocrinology and Metabolism

SN - 0193-1849

IS - 3

ER -