Lessons learned from using fMRI in the early clinical development of a mu-opioid receptor antagonist for disorders of compulsive consumption

Pradeep J. Nathan, Geor Bakker*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

2 Citations (Web of Science)
Original languageEnglish
Pages (from-to)1255-1263
Number of pages9
JournalPsychopharmacology
Volume238
Issue number5
Early online date4 Jan 2020
DOIs
Publication statusPublished - May 2021

Keywords

  • AMYGDALA
  • BEHAVIOR
  • Biomarker
  • Drug development
  • Efficacy
  • Functional magnetic resonance imaging
  • GSK1521498
  • HUMAN BRAIN
  • OCCUPANCY
  • POSITRON-EMISSION-TOMOGRAPHY
  • POWER FAILURE
  • RESPONSES
  • TEST-RETEST RELIABILITY
  • TIME
  • Target engagement
  • fMRI
  • TOOL

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