Less noise, more activation: Multiband acquisition schemes for auditory functional MRI

Federico De Martino*, Michelle Moerel, Kamil Ugurbil, Elia Formisano, Essa Yacoub

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Web of Science)

Abstract

Purpose To improve acquisition in fMRI studies of audition by using multiband (MB) gradient-echo echo planar imaging (GE-EPI). MethodsData were acquired at 3T (Siemens Skyra) with a 32-channel head coil. Functional responses were obtained by presenting stimuli [tones and natural sounds (voices, speech, music, tools, animal cries)] in silent gaps between image acquisitions. Two-fold slice acceleration (MB2) was compared with a standard GE-EPI (MB1). Coverage and sampling rate (TR=3 s) were kept constant across acquisition schemes. The longer gap in MB2 scans was used to present: (i) sounds of the same length as in conventional GE-EPI (type 1; 800 ms stimuli); (ii) sounds of double the length (type 2; 1600 ms stimuli). ResultsFunctional responses to all sounds (i.e., main effect) were stronger when acquired with slice acceleration (i.e., shorter acquisition time). The difference between voice and nonvoice responses was greater in MB2 type 1 acquisitions (i.e., same length sounds as GE-EPI but presented in a longer silent gap) than in standard GE-EPI acquisitions (interaction effect). ConclusionReducing the length of the scanner noise results in stronger functional responses. Longer silent periods (i.e., keeping the sound length the same as in standard acquisitions) result in stronger response to voice compared with nonvoice stimuli. Magn Reson Med 74:462-467, 2015.
Original languageEnglish
Pages (from-to)462-467
JournalMagnetic Resonance in Medicine
Volume74
Issue number2
DOIs
Publication statusPublished - Aug 2015

Keywords

  • GE-EPI
  • auditory fMRI
  • scanner noise

Cite this