Leadless pacing using induction technology: impact of pulse shape and geometric factors on pacing efficiency

Heinrich Wieneke*, Sebastian Rickers, Jonathan Velleuer, Guido Bruck, Zijian Bai, Christian Kocks, Pierre-Andre Grandjean, Tim Lenihan, Peter Jung, Raimund Erbel, Frits W. Prinzen, Erhard Kisker

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Aims Leadless pacing can be done by transmitting energy by an alternating magnetic field from a subcutaneous transmitter unit (TU) to an endocardial receiver unit (RU). Safety and energy consumption are key issues that determine the clinical feasibility of this new technique. The aims of the study were (i) to evaluate the stimulation characteristics of the non-rectangular pacing pulses induced by the alternating magnetic field, (ii) to determine the extent and impact of RU movement caused by the beating heart, and (iii) to evaluate the influence of the relative position between TU and RU on pacing efficiency and energy consumption. Methods and results In the first step pacing efficiency and energy consumption for predefined positions were determined by bench testing. Subsequently, in a goat at five different ventricular sites (three in the right ventricle, two in the left ventricle) pacing thresholds using non-rectangular induction pulses were compared with conventional pulses. Relative position, defined by parallel distance, radial distance, and angulation between TU and RU, were determined in vivo by X-ray and an inclination angle measurement system. Bench testing showed that by magnetic induction for every alignment between TU and RU appropriate pulses can be produced up to a distance of 100 mm. In the animal experiment pacing thresholds were similar for non-rectangular pulses as compared with conventional pulse shapes. In all five positions with distances between 62 and 102 mm effective pacing was obtained in vivo. Variations in distance, displacement and angle caused by the beating heart did not cause loss of capture. At pacing threshold energy consumptions between 0.28 and 5.36 mf were measured. Major determinants of energy consumption were distance and pacing threshold. Conclusion For any given RU position up to a distance of 100 mm reliable pacing using induction can be obtained. In anatomically crucial distances, up to 60 mm energy consumption is within a reasonable range.
Original languageEnglish
Pages (from-to)453-459
JournalEP Europace
Issue number3
Publication statusPublished - Mar 2013


  • Pacemaker
  • Leadless pacing
  • Induction
  • New technology

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