Laser post-ionisation combined with a high resolving power orbitrap mass spectrometer for enhanced MALDI-MS imaging of lipids

S. R. Ellis; J. Soltwisch; M. R. L. Paine; K. Dreisewerd; R. M. A. Heeren

doi:10.1039/c7cc02325a

Laser post-ionisation combined with a high resolving power orbitrap mass spectrometer for enhanced MALDI-MS imaging of lipids

S. R. Ellis^*
, J. Soltwisch
, M. R. L. Paine
, K. Dreisewerd
, R. M. A. Heeren

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

245 Downloads (Pure)

Abstract

Coupling laser post-ionisation with a high resolving power MALDI Orbitrap mass spectrometer has realised an up to B100-fold increase in the sensitivity and enhanced the chemical coverage for MALDI-MS imaging of lipids relative to conventional MALDI. This could constitute a major breakthrough for biomedical research.

Original language	English
Pages (from-to)	7246-7249
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	53
DOIs	https://doi.org/10.1039/c7cc02325a
Publication status	Published - 7 Jul 2017

Keywords

PROTEINS

Access to Document

10.1039/c7cc02325a

Full TextFinal published version, 2.67 MBLicence: Taverne

Cite this

@article{f24d9f7c85e54bfc8544eebb1d320db8,

title = "Laser post-ionisation combined with a high resolving power orbitrap mass spectrometer for enhanced MALDI-MS imaging of lipids",

abstract = "Coupling laser post-ionisation with a high resolving power MALDI Orbitrap mass spectrometer has realised an up to B100-fold increase in the sensitivity and enhanced the chemical coverage for MALDI-MS imaging of lipids relative to conventional MALDI. This could constitute a major breakthrough for biomedical research.",

keywords = "PROTEINS",

author = "Ellis, \{S. R.\} and J. Soltwisch and Paine, \{M. R. L.\} and K. Dreisewerd and Heeren, \{R. M. A.\}",

year = "2017",

month = jul,

day = "7",

doi = "10.1039/c7cc02325a",

language = "English",

volume = "53",

pages = "7246--7249",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "53",

}

TY - JOUR

T1 - Laser post-ionisation combined with a high resolving power orbitrap mass spectrometer for enhanced MALDI-MS imaging of lipids

AU - Ellis, S. R.

AU - Soltwisch, J.

AU - Paine, M. R. L.

AU - Dreisewerd, K.

AU - Heeren, R. M. A.

PY - 2017/7/7

Y1 - 2017/7/7

N2 - Coupling laser post-ionisation with a high resolving power MALDI Orbitrap mass spectrometer has realised an up to B100-fold increase in the sensitivity and enhanced the chemical coverage for MALDI-MS imaging of lipids relative to conventional MALDI. This could constitute a major breakthrough for biomedical research.

AB - Coupling laser post-ionisation with a high resolving power MALDI Orbitrap mass spectrometer has realised an up to B100-fold increase in the sensitivity and enhanced the chemical coverage for MALDI-MS imaging of lipids relative to conventional MALDI. This could constitute a major breakthrough for biomedical research.

KW - PROTEINS

U2 - 10.1039/c7cc02325a

DO - 10.1039/c7cc02325a

M3 - Article

C2 - 28573274

SN - 1359-7345

VL - 53

SP - 7246

EP - 7249

JO - Chemical Communications

JF - Chemical Communications

IS - 53

ER -

Laser post-ionisation combined with a high resolving power orbitrap mass spectrometer for enhanced MALDI-MS imaging of lipids

Abstract

Keywords

Access to Document

Fingerprint

Cite this