Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

U. Vosa*, A. Claringbould*, H.J. Westra, M.J. Bonder, P. Deelen, B. Zeng, H. Kirsten, A. Saha, R. Kreuzhuber, S. Yazar, H. Brugge, R. Oelen, D.H. de Vries, M.G.P. van der Wijst, S. Kasela, N. Pervjakova, I. Alves, M.J. Fave, M. Agbessi, M.W. ChristiansenR. Jansen, I. Seppala, L. Tong, A. Teumer, K. Schramm, G. Hemani, J. Verlouw, H. Yaghootkar, R.S. Flitman, A. Brown, V. Kukushkina, A. Kalnapenkis, S. Rueger, E. Porcu, J. Kronberg, J. Kettunen, B. Lee, F.T. Zhang, T. Qi, J.A. Hernandez, W. Arindrarto, F. Beutner, J. Dmitrieva, M. Elansary, B.P. Fairfax, M. Georges, B.T. Heijmans, A.W. Hewitt, BIOS Consortium, i2QTL Consortium, C.D.A. Stehouwer

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Web of Science)
Original languageEnglish
Pages (from-to)1300-1310
Number of pages22
JournalNature Genetics
Volume53
Issue number9
Early online date2021
DOIs
Publication statusPublished - Sep 2021

Keywords

  • GENOME-WIDE ASSOCIATION
  • SERINE BIOSYNTHESIS
  • HUMAN TRANSCRIPTOME
  • ARCHITECTURE
  • DISEASE
  • DEFICIENCY
  • RELEVANCE
  • DISORDER
  • LINKS
  • RISK

Cite this