Laparoscopic antireflux surgery increases health-related quality of life in children with GERD

Femke A. Mauritz; Rebecca K. Stellato; L. W. Ernst van Heurn; Peter D. Siersema; Cornelius E. J. Sloots; Roderick H. J. Houwen; David C. van der Zee; Maud Y. A. van Herwaarden-Lindeboom

doi:10.1007/s00464-016-5336-5

Laparoscopic antireflux surgery increases health-related quality of life in children with GERD

Femke A. Mauritz^*, Rebecca K. Stellato, L. W. Ernst van Heurn, Peter D. Siersema, Cornelius E. J. Sloots, Roderick H. J. Houwen, David C. van der Zee, Maud Y. A. van Herwaarden-Lindeboom

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Introduction Improving health-related quality of life (HRQoL) is increasingly recognized as an essential part of patient care outcome. Little is known about the effect of laparoscopic antireflux surgery (LARS) on the HRQoL in the pediatric patients. The aims of this study were to evaluate the effect of LARS on HRQoL in children with gastroesophageal reflux disease (GERD) and to identify predictors that influence HRQoL outcome after LARS.

Methods Between 2011 and 2013, 25 patients with therapy-resistant GERD [median age 6 (2-18) years] were included prospectively. Caregivers and children with normal neurodevelopment (>4 years) were asked to fill out the validated PedsQL 4.0 Generic Core Scales before and 3-4 months after LARS.

Results The PedsQL was completed by all caregivers (n = 25) and 12 children. HRQoL total score improved significantly after LARS, both from a parental (p = 0.009) and child's perspective (p = 0.018). The psychosocial health summary and physical health summary scores also improved significantly after LARS. HRQoL before and after LARS was significantly lower in children with impaired neurodevelopment (p

Conclusions HRQoL significantly improves after LARS. Although children with impaired neurodevelopment had lower overall HRQoL, neurodevelopment by itself does not predict inferior improvement in HRQoL after LARS. Older children have a more favorableHRQoL outcome after LARS compared to younger children. This may suggest caution when considering LARS in younger GERD patients.

Original language	English
Pages (from-to)	3122-3129
Number of pages	8
Journal	Surgical endoscopy and other interventional techniques
Volume	31
Issue number	8
DOIs	https://doi.org/10.1007/s00464-016-5336-5
Publication status	Published - Aug 2017

Keywords

Pediatric
Children
Reflux
GERD
Fundoplication
Quality of life
Antireflux surgery
GASTROESOPHAGEAL-REFLUX DISEASE
NISSEN FUNDOPLICATION
PEDIATRIC POPULATION
RELIABILITY
VALIDITY
PH
PEDSQL(TM)-4.0
SATISFACTION
FEASIBILITY
INFANTS

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Cite this

Mauritz, F. A., Stellato, R. K., van Heurn, L. W. E., Siersema, P. D., Sloots, C. E. J., Houwen, R. H. J., van der Zee, D. C., & van Herwaarden-Lindeboom, M. Y. A. (2017). Laparoscopic antireflux surgery increases health-related quality of life in children with GERD. Surgical endoscopy and other interventional techniques, 31(8), 3122-3129. https://doi.org/10.1007/s00464-016-5336-5

@article{9fb2c256eae1487a9070e859f5f1b98c,

title = "Laparoscopic antireflux surgery increases health-related quality of life in children with GERD",

abstract = "Introduction Improving health-related quality of life (HRQoL) is increasingly recognized as an essential part of patient care outcome. Little is known about the effect of laparoscopic antireflux surgery (LARS) on the HRQoL in the pediatric patients. The aims of this study were to evaluate the effect of LARS on HRQoL in children with gastroesophageal reflux disease (GERD) and to identify predictors that influence HRQoL outcome after LARS.Methods Between 2011 and 2013, 25 patients with therapy-resistant GERD [median age 6 (2-18) years] were included prospectively. Caregivers and children with normal neurodevelopment (>4 years) were asked to fill out the validated PedsQL 4.0 Generic Core Scales before and 3-4 months after LARS.Results The PedsQL was completed by all caregivers (n = 25) and 12 children. HRQoL total score improved significantly after LARS, both from a parental (p = 0.009) and child's perspective (p = 0.018). The psychosocial health summary and physical health summary scores also improved significantly after LARS. HRQoL before and after LARS was significantly lower in children with impaired neurodevelopment (pConclusions HRQoL significantly improves after LARS. Although children with impaired neurodevelopment had lower overall HRQoL, neurodevelopment by itself does not predict inferior improvement in HRQoL after LARS. Older children have a more favorableHRQoL outcome after LARS compared to younger children. This may suggest caution when considering LARS in younger GERD patients.",

keywords = "Pediatric, Children, Reflux, GERD, Fundoplication, Quality of life, Antireflux surgery, GASTROESOPHAGEAL-REFLUX DISEASE, NISSEN FUNDOPLICATION, PEDIATRIC POPULATION, RELIABILITY, VALIDITY, PH, PEDSQL(TM)-4.0, SATISFACTION, FEASIBILITY, INFANTS",

author = "Mauritz, {Femke A.} and Stellato, {Rebecca K.} and {van Heurn}, {L. W. Ernst} and Siersema, {Peter D.} and Sloots, {Cornelius E. J.} and Houwen, {Roderick H. J.} and {van der Zee}, {David C.} and {van Herwaarden-Lindeboom}, {Maud Y. A.}",

year = "2017",

month = aug,

doi = "10.1007/s00464-016-5336-5",

language = "English",

volume = "31",

pages = "3122--3129",

journal = "Surgical endoscopy and other interventional techniques",

issn = "0930-2794",

publisher = "Springer, Cham",

number = "8",

}

TY - JOUR

T1 - Laparoscopic antireflux surgery increases health-related quality of life in children with GERD

AU - Mauritz, Femke A.

AU - Stellato, Rebecca K.

AU - van Heurn, L. W. Ernst

AU - Siersema, Peter D.

AU - Sloots, Cornelius E. J.

AU - Houwen, Roderick H. J.

AU - van der Zee, David C.

AU - van Herwaarden-Lindeboom, Maud Y. A.

PY - 2017/8

Y1 - 2017/8

N2 - Introduction Improving health-related quality of life (HRQoL) is increasingly recognized as an essential part of patient care outcome. Little is known about the effect of laparoscopic antireflux surgery (LARS) on the HRQoL in the pediatric patients. The aims of this study were to evaluate the effect of LARS on HRQoL in children with gastroesophageal reflux disease (GERD) and to identify predictors that influence HRQoL outcome after LARS.Methods Between 2011 and 2013, 25 patients with therapy-resistant GERD [median age 6 (2-18) years] were included prospectively. Caregivers and children with normal neurodevelopment (>4 years) were asked to fill out the validated PedsQL 4.0 Generic Core Scales before and 3-4 months after LARS.Results The PedsQL was completed by all caregivers (n = 25) and 12 children. HRQoL total score improved significantly after LARS, both from a parental (p = 0.009) and child's perspective (p = 0.018). The psychosocial health summary and physical health summary scores also improved significantly after LARS. HRQoL before and after LARS was significantly lower in children with impaired neurodevelopment (pConclusions HRQoL significantly improves after LARS. Although children with impaired neurodevelopment had lower overall HRQoL, neurodevelopment by itself does not predict inferior improvement in HRQoL after LARS. Older children have a more favorableHRQoL outcome after LARS compared to younger children. This may suggest caution when considering LARS in younger GERD patients.

AB - Introduction Improving health-related quality of life (HRQoL) is increasingly recognized as an essential part of patient care outcome. Little is known about the effect of laparoscopic antireflux surgery (LARS) on the HRQoL in the pediatric patients. The aims of this study were to evaluate the effect of LARS on HRQoL in children with gastroesophageal reflux disease (GERD) and to identify predictors that influence HRQoL outcome after LARS.Methods Between 2011 and 2013, 25 patients with therapy-resistant GERD [median age 6 (2-18) years] were included prospectively. Caregivers and children with normal neurodevelopment (>4 years) were asked to fill out the validated PedsQL 4.0 Generic Core Scales before and 3-4 months after LARS.Results The PedsQL was completed by all caregivers (n = 25) and 12 children. HRQoL total score improved significantly after LARS, both from a parental (p = 0.009) and child's perspective (p = 0.018). The psychosocial health summary and physical health summary scores also improved significantly after LARS. HRQoL before and after LARS was significantly lower in children with impaired neurodevelopment (pConclusions HRQoL significantly improves after LARS. Although children with impaired neurodevelopment had lower overall HRQoL, neurodevelopment by itself does not predict inferior improvement in HRQoL after LARS. Older children have a more favorableHRQoL outcome after LARS compared to younger children. This may suggest caution when considering LARS in younger GERD patients.

KW - Pediatric

KW - Children

KW - Reflux

KW - GERD

KW - Fundoplication

KW - Quality of life

KW - Antireflux surgery

KW - GASTROESOPHAGEAL-REFLUX DISEASE

KW - NISSEN FUNDOPLICATION

KW - PEDIATRIC POPULATION

KW - RELIABILITY

KW - VALIDITY

KW - PH

KW - PEDSQL(TM)-4.0

KW - SATISFACTION

KW - FEASIBILITY

KW - INFANTS

U2 - 10.1007/s00464-016-5336-5

DO - 10.1007/s00464-016-5336-5

M3 - Article

C2 - 27864715

SN - 0930-2794

VL - 31

SP - 3122

EP - 3129

JO - Surgical endoscopy and other interventional techniques

JF - Surgical endoscopy and other interventional techniques

IS - 8

ER -