Lacosamide in patients with Na(v)1.7 mutations-related small fibre neuropathy: a randomized controlled trial

Bianca T. A. de Greef; Janneke G. J. Hoeijmakers; Margot Geerts; Mike Oakes; Tim J. E. Church; Stephen G. Waxman; Sulayman D. Dib-Hajj; Catharina G. Faber; Ingemar S. J. Merkies

doi:10.1093/brain/awy329

Lacosamide in patients with Na(v)1.7 mutations-related small fibre neuropathy: a randomized controlled trial

Bianca T. A. de Greef^*, Janneke G. J. Hoeijmakers, Margot Geerts, Mike Oakes, Tim J. E. Church, Stephen G. Waxman, Sulayman D. Dib-Hajj, Catharina G. Faber, Ingemar S. J. Merkies

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	263-275
Number of pages	13
Journal	Brain
Volume	142
DOIs	https://doi.org/10.1093/brain/awy329
Publication status	Published - Feb 2019

Keywords

small fibre neuropathy
lacosamide
Na(v)1
7 mutations
neuropathic pain
RCT
SODIUM-CHANNELS
SLOW-INACTIVATION
DOUBLE-BLIND
PAIN
EFFICACY
SAFETY
PATHOPHYSIOLOGY
CRMP2

Cite this

de Greef, B. T. A., Hoeijmakers, J. G. J., Geerts, M., Oakes, M., Church, T. J. E., Waxman, S. G., Dib-Hajj, S. D., Faber, C. G., & Merkies, I. S. J. (2019). Lacosamide in patients with Na(v)1.7 mutations-related small fibre neuropathy: a randomized controlled trial. Brain, 142, 263-275. https://doi.org/10.1093/brain/awy329

@article{3633f07c77c44156982c986c085d8a7f,

title = "Lacosamide in patients with Na(v)1.7 mutations-related small fibre neuropathy: a randomized controlled trial",

keywords = "small fibre neuropathy, lacosamide, Na(v)1, 7 mutations, neuropathic pain, RCT, SODIUM-CHANNELS, SLOW-INACTIVATION, DOUBLE-BLIND, PAIN, EFFICACY, SAFETY, PATHOPHYSIOLOGY, CRMP2",

author = "{de Greef}, {Bianca T. A.} and Hoeijmakers, {Janneke G. J.} and Margot Geerts and Mike Oakes and Church, {Tim J. E.} and Waxman, {Stephen G.} and Dib-Hajj, {Sulayman D.} and Faber, {Catharina G.} and Merkies, {Ingemar S. J.}",

year = "2019",

month = feb,

doi = "10.1093/brain/awy329",

language = "English",

volume = "142",

pages = "263--275",

journal = "Brain",

issn = "0006-8950",

publisher = "Oxford University Press",

}

Lacosamide in patients with Na(v)1.7 mutations-related small fibre neuropathy : a randomized controlled trial. / de Greef, Bianca T. A.; Hoeijmakers, Janneke G. J.; Geerts, Margot; Oakes, Mike; Church, Tim J. E.; Waxman, Stephen G.; Dib-Hajj, Sulayman D.; Faber, Catharina G.; Merkies, Ingemar S. J.

In: Brain, Vol. 142, 02.2019, p. 263-275.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Lacosamide in patients with Na(v)1.7 mutations-related small fibre neuropathy

T2 - a randomized controlled trial

AU - de Greef, Bianca T. A.

AU - Hoeijmakers, Janneke G. J.

AU - Geerts, Margot

AU - Oakes, Mike

AU - Church, Tim J. E.

AU - Waxman, Stephen G.

AU - Dib-Hajj, Sulayman D.

AU - Faber, Catharina G.

AU - Merkies, Ingemar S. J.

PY - 2019/2

Y1 - 2019/2

KW - small fibre neuropathy

KW - lacosamide

KW - Na(v)1

KW - 7 mutations

KW - neuropathic pain

KW - RCT

KW - SODIUM-CHANNELS

KW - SLOW-INACTIVATION

KW - DOUBLE-BLIND

KW - PAIN

KW - EFFICACY

KW - SAFETY

KW - PATHOPHYSIOLOGY

KW - CRMP2

U2 - 10.1093/brain/awy329

DO - 10.1093/brain/awy329

M3 - Article

VL - 142

SP - 263

EP - 275

JO - Brain

JF - Brain

SN - 0006-8950

ER -

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10.1093/brain/awy329