Lack of PIVKA effect in the abnormal factor X (factor X friuli) coagulation disorder

A. Girolami, A.D. Muller, H.C. Hemker

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    Abstract

    Thrombotest dilution curves and specific inhibitor experiments were carried out in the abnormal factor X (factor X Friuli) plasma and in coumarin plasma. Thrombotest dilution curves obtained with Friuli plasma suggested the presence of a PIVKA-like inhibitor which was not confirmed by the specific experiments. The inhibitory capacity found in Friuli plasma was-0.09 arbitrary units, whereas that found in coumarin-treated patients with a factor X level ranging from 1 to 14% varied between 0.34 and 0.21 arbitrary units.
    Original languageEnglish
    Pages (from-to)23-30
    Number of pages8
    JournalHaemostasis
    Volume1
    Issue number1
    DOIs
    Publication statusPublished - 1972

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