Knockout of Mitochondrial Thioredoxin Reductase Stabilizes Prolyl Hydroxylase 2 and Inhibits Tumor Growth and Tumor-Derived Angiogenesis

Juliane Hellfritsch; Julian Kirsch; Manuela Schneider; Tamara Fluege; Markus Wortmann; Jeroen Frijhoff; Markus Dagnell; Theres Fey; Irene Esposito; Pirkko Koelle; Kristin Pogoda; Jose Pedro Friedmann Angeli; Irina Ingold; Peter Kuhlencordt; Arne Ostman; Ulrich Pohl; Marcus Conrad; Heike Beck

doi:10.1089/ars.2014.5889

Knockout of Mitochondrial Thioredoxin Reductase Stabilizes Prolyl Hydroxylase 2 and Inhibits Tumor Growth and Tumor-Derived Angiogenesis

Juliane Hellfritsch, Julian Kirsch, Manuela Schneider, Tamara Fluege, Markus Wortmann, Jeroen Frijhoff, Markus Dagnell, Theres Fey, Irene Esposito, Pirkko Koelle, Kristin Pogoda, Jose Pedro Friedmann Angeli, Irina Ingold, Peter Kuhlencordt, Arne Ostman, Ulrich Pohl, Marcus Conrad, Heike Beck

Pharmacology and Personalised Medicine

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	938-950
Journal	Antioxidants & Redox Signaling
Volume	22
Issue number	11
DOIs	https://doi.org/10.1089/ars.2014.5889
Publication status	Published - 10 Apr 2015

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10.1089/ars.2014.5889

Cite this

Hellfritsch, J., Kirsch, J., Schneider, M., Fluege, T., Wortmann, M., Frijhoff, J., Dagnell, M., Fey, T., Esposito, I., Koelle, P., Pogoda, K., Angeli, J. P. F., Ingold, I., Kuhlencordt, P., Ostman, A., Pohl, U., Conrad, M., & Beck, H. (2015). Knockout of Mitochondrial Thioredoxin Reductase Stabilizes Prolyl Hydroxylase 2 and Inhibits Tumor Growth and Tumor-Derived Angiogenesis. Antioxidants & Redox Signaling, 22(11), 938-950. https://doi.org/10.1089/ars.2014.5889

Hellfritsch, Juliane ; Kirsch, Julian ; Schneider, Manuela ; Fluege, Tamara ; Wortmann, Markus ; Frijhoff, Jeroen ; Dagnell, Markus ; Fey, Theres ; Esposito, Irene ; Koelle, Pirkko ; Pogoda, Kristin ; Angeli, Jose Pedro Friedmann ; Ingold, Irina ; Kuhlencordt, Peter ; Ostman, Arne ; Pohl, Ulrich ; Conrad, Marcus ; Beck, Heike. / Knockout of Mitochondrial Thioredoxin Reductase Stabilizes Prolyl Hydroxylase 2 and Inhibits Tumor Growth and Tumor-Derived Angiogenesis. In: Antioxidants & Redox Signaling. 2015 ; Vol. 22, No. 11. pp. 938-950.

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title = "Knockout of Mitochondrial Thioredoxin Reductase Stabilizes Prolyl Hydroxylase 2 and Inhibits Tumor Growth and Tumor-Derived Angiogenesis",

author = "Juliane Hellfritsch and Julian Kirsch and Manuela Schneider and Tamara Fluege and Markus Wortmann and Jeroen Frijhoff and Markus Dagnell and Theres Fey and Irene Esposito and Pirkko Koelle and Kristin Pogoda and Angeli, {Jose Pedro Friedmann} and Irina Ingold and Peter Kuhlencordt and Arne Ostman and Ulrich Pohl and Marcus Conrad and Heike Beck",

year = "2015",

month = apr,

day = "10",

doi = "10.1089/ars.2014.5889",

language = "English",

volume = "22",

pages = "938--950",

journal = "Antioxidants & Redox Signaling",

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Hellfritsch, J, Kirsch, J, Schneider, M, Fluege, T, Wortmann, M, Frijhoff, J, Dagnell, M, Fey, T, Esposito, I, Koelle, P, Pogoda, K, Angeli, JPF, Ingold, I, Kuhlencordt, P, Ostman, A, Pohl, U, Conrad, M & Beck, H 2015, 'Knockout of Mitochondrial Thioredoxin Reductase Stabilizes Prolyl Hydroxylase 2 and Inhibits Tumor Growth and Tumor-Derived Angiogenesis', Antioxidants & Redox Signaling, vol. 22, no. 11, pp. 938-950. https://doi.org/10.1089/ars.2014.5889

Knockout of Mitochondrial Thioredoxin Reductase Stabilizes Prolyl Hydroxylase 2 and Inhibits Tumor Growth and Tumor-Derived Angiogenesis. / Hellfritsch, Juliane; Kirsch, Julian; Schneider, Manuela; Fluege, Tamara; Wortmann, Markus; Frijhoff, Jeroen; Dagnell, Markus; Fey, Theres; Esposito, Irene; Koelle, Pirkko; Pogoda, Kristin; Angeli, Jose Pedro Friedmann; Ingold, Irina; Kuhlencordt, Peter; Ostman, Arne; Pohl, Ulrich; Conrad, Marcus; Beck, Heike.

In: Antioxidants & Redox Signaling, Vol. 22, No. 11, 10.04.2015, p. 938-950.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Knockout of Mitochondrial Thioredoxin Reductase Stabilizes Prolyl Hydroxylase 2 and Inhibits Tumor Growth and Tumor-Derived Angiogenesis

AU - Hellfritsch, Juliane

AU - Kirsch, Julian

AU - Schneider, Manuela

AU - Fluege, Tamara

AU - Wortmann, Markus

AU - Frijhoff, Jeroen

AU - Dagnell, Markus

AU - Fey, Theres

AU - Esposito, Irene

AU - Koelle, Pirkko

AU - Pogoda, Kristin

AU - Angeli, Jose Pedro Friedmann

AU - Ingold, Irina

AU - Kuhlencordt, Peter

AU - Ostman, Arne

AU - Pohl, Ulrich

AU - Conrad, Marcus

AU - Beck, Heike

PY - 2015/4/10

Y1 - 2015/4/10

U2 - 10.1089/ars.2014.5889

DO - 10.1089/ars.2014.5889

M3 - Article

C2 - 25647640

VL - 22

SP - 938

EP - 950

JO - Antioxidants & Redox Signaling

JF - Antioxidants & Redox Signaling

SN - 1523-0864

IS - 11

ER -