Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability

Andreas Blana; Sven Kaese; Lisa Fortmueller; Sandra Laakmann; Dierk Damke; Kelly van Bragt; Jens Eckstein; Ilaria Piccini; Uwe Kirchhefer; Stanley Nattel; Guenter Breithardt; Peter Carmeliet; Edward Carmeliet; Ulrich Schotten; Sander Verheule; Paulus Kirchhof; Larissa Fabritz

doi:10.1016/j.hrthm.2010.08.016

Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability

Andreas Blana, Sven Kaese, Lisa Fortmueller, Sandra Laakmann, Dierk Damke, Kelly van Bragt, Jens Eckstein, Ilaria Piccini, Uwe Kirchhefer, Stanley Nattel, Guenter Breithardt, Peter Carmeliet, Edward Carmeliet, Ulrich Schotten, Sander Verheule, Paulus Kirchhof, Larissa Fabritz^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

41 Citations (Web of Science)

Original language	English
Pages (from-to)	1862-1869
Journal	Heart Rhythm
Volume	7
Issue number	12
DOIs	https://doi.org/10.1016/j.hrthm.2010.08.016
Publication status	Published - Dec 2010

Keywords

Antiarrhythmic drugs
Atrial remodeling
Electrophysiology
Genetic models
Nav1.5

Access to Document

10.1016/j.hrthm.2010.08.016

Cite this

Blana, A., Kaese, S., Fortmueller, L., Laakmann, S., Damke, D., van Bragt, K., Eckstein, J., Piccini, I., Kirchhefer, U., Nattel, S., Breithardt, G., Carmeliet, P., Carmeliet, E., Schotten, U., Verheule, S., Kirchhof, P., & Fabritz, L. (2010). Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability. Heart Rhythm, 7(12), 1862-1869. https://doi.org/10.1016/j.hrthm.2010.08.016

Blana, Andreas ; Kaese, Sven ; Fortmueller, Lisa ; Laakmann, Sandra ; Damke, Dierk ; van Bragt, Kelly ; Eckstein, Jens ; Piccini, Ilaria ; Kirchhefer, Uwe ; Nattel, Stanley ; Breithardt, Guenter ; Carmeliet, Peter ; Carmeliet, Edward ; Schotten, Ulrich ; Verheule, Sander ; Kirchhof, Paulus ; Fabritz, Larissa. / Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability. In: Heart Rhythm. 2010 ; Vol. 7, No. 12. pp. 1862-1869.

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title = "Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability",

keywords = "Antiarrhythmic drugs, Atrial remodeling, Electrophysiology, Genetic models, Nav1.5",

author = "Andreas Blana and Sven Kaese and Lisa Fortmueller and Sandra Laakmann and Dierk Damke and {van Bragt}, Kelly and Jens Eckstein and Ilaria Piccini and Uwe Kirchhefer and Stanley Nattel and Guenter Breithardt and Peter Carmeliet and Edward Carmeliet and Ulrich Schotten and Sander Verheule and Paulus Kirchhof and Larissa Fabritz",

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Blana, A, Kaese, S, Fortmueller, L, Laakmann, S, Damke, D, van Bragt, K, Eckstein, J, Piccini, I, Kirchhefer, U, Nattel, S, Breithardt, G, Carmeliet, P, Carmeliet, E, Schotten, U , Verheule, S, Kirchhof, P & Fabritz, L 2010, 'Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability', Heart Rhythm, vol. 7, no. 12, pp. 1862-1869. https://doi.org/10.1016/j.hrthm.2010.08.016

Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability. / Blana, Andreas; Kaese, Sven; Fortmueller, Lisa; Laakmann, Sandra; Damke, Dierk; van Bragt, Kelly; Eckstein, Jens; Piccini, Ilaria; Kirchhefer, Uwe; Nattel, Stanley; Breithardt, Guenter; Carmeliet, Peter; Carmeliet, Edward; Schotten, Ulrich ; Verheule, Sander; Kirchhof, Paulus; Fabritz, Larissa.

In: Heart Rhythm, Vol. 7, No. 12, 12.2010, p. 1862-1869.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability

AU - Blana, Andreas

AU - Kaese, Sven

AU - Fortmueller, Lisa

AU - Laakmann, Sandra

AU - Damke, Dierk

AU - van Bragt, Kelly

AU - Eckstein, Jens

AU - Piccini, Ilaria

AU - Kirchhefer, Uwe

AU - Nattel, Stanley

AU - Breithardt, Guenter

AU - Carmeliet, Peter

AU - Carmeliet, Edward

AU - Schotten, Ulrich

AU - Verheule, Sander

AU - Kirchhof, Paulus

AU - Fabritz, Larissa

PY - 2010/12

Y1 - 2010/12

KW - Antiarrhythmic drugs

KW - Atrial remodeling

KW - Electrophysiology

KW - Genetic models

KW - Nav1.5

U2 - 10.1016/j.hrthm.2010.08.016

DO - 10.1016/j.hrthm.2010.08.016

M3 - Article

C2 - 20728579

VL - 7

SP - 1862

EP - 1869

JO - Heart Rhythm

JF - Heart Rhythm

SN - 1547-5271

IS - 12

ER -