Abstract
Maintaining healthy knees is crucial for mobility and quality of life. This thesis explores how to preserve the knee joint, especially in middle-aged patients who often fall between regenerative and replacement options. It presents a modified surgical technique for reattaching cartilage fragments in young patients, showing excellent healing and full return to sports. A review of existing treatments found that microfracture procedures perform poorly in older patients, while bone-based methods such as osteochondral grafts and focal knee resurfacing implants (FKRIs) show better long-term results. A national survey revealed that many Dutch surgeons still use outdated treatments, highlighting the need for better education and guideline adherence. Finally, the thesis introduces a new implant made from polycarbonate-urethane (PCU) and zirconium oxide, offering a durable, MRI-compatible alternative to metal implants. Overall, it emphasizes smarter, age-specific strategies to delay or prevent knee replacement surgery.
| Original language | English |
|---|---|
| Qualification | Doctor of Philosophy |
| Awarding Institution |
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| Supervisors/Advisors |
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| Award date | 19 Dec 2025 |
| Place of Publication | Maastricht |
| Publication status | Published - 19 Dec 2025 |
Keywords
- Cartilage
- Joint Preservation
- Knee
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