Key Characteristics Approach to Carcinogenic Hazard Identification

Kathryn Z Guyton, Linda Rieswijk, Amy Wang, Weihsueh A Chiu, Martyn T Smith

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Evaluating carcinogenic mechanisms is a challenging part of hazard identification, as mechanistic data are both voluminous and diverse. An evaluation approach based on 10 key characteristics of human carcinogens provides a holistic and unbiased way to tackle this challenge.

Original languageEnglish
Pages (from-to)1290-1292
Number of pages3
JournalChemical Research in Toxicology
Volume31
Issue number12
DOIs
Publication statusPublished - 17 Dec 2018

Cite this

Guyton, Kathryn Z ; Rieswijk, Linda ; Wang, Amy ; Chiu, Weihsueh A ; Smith, Martyn T. / Key Characteristics Approach to Carcinogenic Hazard Identification. In: Chemical Research in Toxicology. 2018 ; Vol. 31, No. 12. pp. 1290-1292.
@article{a8b01bd3412c4bd4a649891d394353b0,
title = "Key Characteristics Approach to Carcinogenic Hazard Identification",
abstract = "Evaluating carcinogenic mechanisms is a challenging part of hazard identification, as mechanistic data are both voluminous and diverse. An evaluation approach based on 10 key characteristics of human carcinogens provides a holistic and unbiased way to tackle this challenge.",
author = "Guyton, {Kathryn Z} and Linda Rieswijk and Amy Wang and Chiu, {Weihsueh A} and Smith, {Martyn T}",
year = "2018",
month = "12",
day = "17",
doi = "10.1021/acs.chemrestox.8b00321",
language = "English",
volume = "31",
pages = "1290--1292",
journal = "Chemical Research in Toxicology",
issn = "0893-228X",
publisher = "American Chemical Society",
number = "12",

}

Key Characteristics Approach to Carcinogenic Hazard Identification. / Guyton, Kathryn Z; Rieswijk, Linda; Wang, Amy; Chiu, Weihsueh A; Smith, Martyn T.

In: Chemical Research in Toxicology, Vol. 31, No. 12, 17.12.2018, p. 1290-1292.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Key Characteristics Approach to Carcinogenic Hazard Identification

AU - Guyton, Kathryn Z

AU - Rieswijk, Linda

AU - Wang, Amy

AU - Chiu, Weihsueh A

AU - Smith, Martyn T

PY - 2018/12/17

Y1 - 2018/12/17

N2 - Evaluating carcinogenic mechanisms is a challenging part of hazard identification, as mechanistic data are both voluminous and diverse. An evaluation approach based on 10 key characteristics of human carcinogens provides a holistic and unbiased way to tackle this challenge.

AB - Evaluating carcinogenic mechanisms is a challenging part of hazard identification, as mechanistic data are both voluminous and diverse. An evaluation approach based on 10 key characteristics of human carcinogens provides a holistic and unbiased way to tackle this challenge.

U2 - 10.1021/acs.chemrestox.8b00321

DO - 10.1021/acs.chemrestox.8b00321

M3 - Article

C2 - 30521319

VL - 31

SP - 1290

EP - 1292

JO - Chemical Research in Toxicology

JF - Chemical Research in Toxicology

SN - 0893-228X

IS - 12

ER -