IVF, from the past to the future: the inheritance of the Capri Workshop Group

Annual Capri Workshop Group, John Dumoulin

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Web of Science)

Abstract

Today IVF use is booming all over the world and has even started to play a role in demographic analyses. Prognosis-adjusted estimates suggest that up to two-thirds of couples could achieve a live birth. However, the scenario is less exciting in reality. Discontinuation during the cycles is common, and age and ovarian response continue to be crucial in modulating this rate of success. A growing interest is now given to the risk of abuses and in particular to overtreatment and to prescriptions of useless, if not harmful, expensive additional treatments ('add-ons'). A more rational, evidence-based and wise approach is needed. From a scientific perspective, several obscure aspects remain and warrant future investigations. Of particular interest are the neglected role of sperm selection, the potential adult implications of early embryo life in vitro and the issue of sustainability.

Original languageEnglish
Article numberhoaa040
Number of pages9
JournalHuman reproduction open
Volume2020
Issue number3
DOIs
Publication statusPublished - 2020

Keywords

  • IVF
  • ICSI
  • preimplantation genetic testing for aneuploidies
  • epigenetics
  • developmental origins of health and disease
  • IUI
  • sperm
  • drop-out
  • IN-VITRO FERTILIZATION
  • ADVANCED MATERNAL AGE
  • PREIMPLANTATION GENETIC DIAGNOSIS
  • LIVE-BIRTH
  • EMBRYO-TRANSFER
  • FROZEN EMBRYOS
  • OVARIAN STIMULATION
  • BLASTOCYST TRANSFER
  • SPERM INJECTION
  • OOCYTES

Cite this