IVF culture medium and long-term child development

Research output: ThesisDoctoral ThesisInternal

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In an IVF treatment, embryos are grown for 2-3 days in a culture fluid. Previous studies have shown that a short stay in this fluid has an effect on the birthweight of the child born 9 months later. In this thesis, it was exammined whether the culture fluid has a long-term effect on the development of IVF-children. This indeed turned out to be the case: at the age of nine, children who spent several days in one medium as an embryo weighed one and a half kilos heavier than in another medium. Small embryonic changes may therefore potentially affect health in later life.
Original languageEnglish
Awarding Institution
  • Maastricht University
  • Evers, Johannes, Supervisor
  • van Montfoort, Aafke, Co-Supervisor
  • Dumoulin, John, Co-Supervisor
Award date1 Feb 2019
Place of PublicationMaastricht
Print ISBNs9789463800969
Publication statusPublished - 2019


  • IVF
  • ICSI
  • Fertility
  • culture medium
  • Follow-up

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