Is visceral flow during intra-aortic balloon pumping size or volume dependent?

Sandro Gelsomino*, Pieter W. J. Lozekoot, Monique M. J. de Jong, Fabiana Luca, Orlando Parise, Francesco Matteucci, Mario Romano, Abdullrazak Hossien, Mark La Meir, Niccolo Marchionni, Jos G. Maessen, Roberto Lorusso

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Aim: We evaluated the influence of intra-aortic balloon size and volume on mesenteric and renal flows.

Methods: Thirty healthy swine underwent 120-minute ligation of the left anterior descending coronary artery followed by 6 hours of reperfusion. Then, they were randomly assigned to the following five groups of animals, with six animals in each group: no intra-aortic balloon pump (IABP), a short 35-mL IABP, a short 40-mL IABP, a long 35-mL IABP and a long 40-mL IABP. Superior mesenteric artery (SMA) and renal flows were measured at baseline (t(0)), at 2-hour ischemia (t(1)) and every hour thereafter until 6 hours of reperfusion (from t(R1) to t(R6)).

Results: SMA flows increased significantly at t(R1) only in the two short IABP groups (p0.05). Renal flows appeared to be influenced by balloon length, but not by volume. Indeed, flows in the renal arteries rose during IABP treatment; the increase was significantly higher in the short balloon groups and throughout the whole reperfusion (all, p

Conclusions: Changes in visceral perfusion during IABP assistance were significantly related to balloon length, but not to its volume. This could be relevant for the evolution of balloon engineering design in order to reduce the incidence of mesenteric ischemia following IABP. Further research is necessary to confirm these findings.

Original languageEnglish
Pages (from-to)285-295
Number of pages11
JournalPerfusion
Volume32
Issue number4
DOIs
Publication statusPublished - May 2017

Keywords

  • intra-aortic balloon counterpulsation
  • intra-aortic balloon pump
  • visceral flow
  • myocardial ischemia
  • myocardial infarction
  • CARDIAC CONTRACTILE EFFICIENCY
  • RENAL BLOOD-FLOW
  • CARDIOPULMONARY BYPASS
  • MYOCARDIAL-ISCHEMIA
  • PORCINE MODEL
  • ANIMAL-MODEL
  • COUNTERPULSATION
  • ARTERY
  • RISK
  • HEMODYNAMICS

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