Is cardiovascular disease in PCOS driven by MASLD?

Huadong Chen; Pomme I.H.G. Simons; Martijn C.G.J. Brouwers

doi:10.1016/j.tem.2024.10.005

Is cardiovascular disease in PCOS driven by MASLD?

Huadong Chen, Pomme I.H.G. Simons, Martijn C.G.J. Brouwers^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Recent genetic studies have implicated an active role for intrahepatic lipid accumulation in the pathogenesis of both polycystic ovary syndrome (PCOS) and cardiovascular disease. These new insights may provide novel (non)pharmacological opportunities for the prevention and treatment of PCOS and cardiovascular disease at both the societal and clinical level.

Original language	English
Journal	Trends in Endocrinology and Metabolism
DOIs	https://doi.org/10.1016/j.tem.2024.10.005
Publication status	E-pub ahead of print - 1 Jan 2024

Keywords

cardiovascular disease (CVD)
fructose
MASLD
Mendelian randomization
PCOS
triangulation

Access to Document

10.1016/j.tem.2024.10.005

Cite this

@article{2ae7d813c9104cfd991707e6bf56c1a4,

title = "Is cardiovascular disease in PCOS driven by MASLD?",

abstract = "Recent genetic studies have implicated an active role for intrahepatic lipid accumulation in the pathogenesis of both polycystic ovary syndrome (PCOS) and cardiovascular disease. These new insights may provide novel (non)pharmacological opportunities for the prevention and treatment of PCOS and cardiovascular disease at both the societal and clinical level.",

keywords = "cardiovascular disease (CVD), fructose, MASLD, Mendelian randomization, PCOS, triangulation",

author = "Huadong Chen and Simons, {Pomme I.H.G.} and Brouwers, {Martijn C.G.J.}",

note = "Publisher Copyright: {\textcopyright} 2024 Elsevier Ltd",

year = "2024",

month = jan,

day = "1",

doi = "10.1016/j.tem.2024.10.005",

language = "English",

journal = "Trends in Endocrinology and Metabolism",