Intra-aortic balloon pump: Looking at the other side

Sandro Gelsomino*, Monique M. J. de Jong

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Intra-aortic balloon pump has been the most commonly employed cardiac assist device in the past, although, in recent years, its use in cardiogenic shock has been questioned. The pathophysiology of the proximal part of the balloon has been well studied, whereas, hemodynamics and flow below the distal portion of the balloon have not been fully understood yet. The distal flow contains a three-wave flow pattern during diastolic balloon expansion: a flow reduction in early diastole, a backflow in mid-diastole followed by a tele-diastolic flow. More research on this topic is warranted to better understand the physics of the distal part of the balloon and its interaction with the three components of the local regulatory system: intrinsic (local metabolic and myogenic), extrinsic (autonomic nervous system), and humoral (local or circulating vasoactive substances). These new insights will be a guide for new balloon designs that will allow enhanced performance and improved outcomes.

Original languageEnglish
Pages (from-to)159-162
Number of pages4
JournalArtificial Organs
Issue number2
Early online date23 Oct 2020
Publication statusPublished - Feb 2021


  • abdominal flow
  • circulation
  • intra&#8208
  • aortic balloon
  • FLOW

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