Interprofessional Consensus Regarding Design Requirements for Liquid-Based Perinatal Life Support (PLS) Technology

M.B.V. van der Jagt*, E.J.T. Verweij, P. Andriessen, W.P. de Boode, A.F. Bos, F.L.M. Delbressine, A.J. Eggink, J.J.H.M. Erwich, L.M.G. Feijs, F. Groenendaal, B.W.W. Kramer, A.T. Lely, R.F.A.M. Loop, F. Neukamp, W. Onland, M.A. Oudijk, A.B. te Pas, I.K.M. Reiss, M. Schoberer, R.R. ScholtenM.E.A. Spaanderman, M. van der Ven, M.J. Vermeulen, F.N. van de Vosse, S.G. Oei, Dutch Consortium, PLS Consortium

*Corresponding author for this work

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Liquid-based perinatal life support (PLS) technology will probably be applied in a first-in-human study within the next decade. Research and development of PLS technology should not only address technical issues, but also consider socio-ethical and legal aspects, its application area, and the corresponding design implications. This paper represents the consensus opinion of a group of healthcare professionals, designers, ethicists, researchers and patient representatives, who have expertise in tertiary obstetric and neonatal care, bio-ethics, experimental perinatal animal models for physiologic research, biomedical modeling, monitoring, and design. The aim of this paper is to provide a framework for research and development of PLS technology. These requirements are considering the possible respective user perspectives, with the aim to co-create a PLS system that facilitates physiological growth and development for extremely preterm born infants.
Original languageEnglish
Article number793531
Number of pages8
JournalFrontiers in pediatrics
Publication statusPublished - 19 Jan 2022


  • perinatal life support
  • artificial placenta
  • AAPT
  • user perspectives
  • design implications
  • value-sensitive design

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