TY - JOUR
T1 - International Society of Geriatric Oncology Consensus on Geriatric Assessment in Older Patients With Cancer
AU - Wildiers, Hans
AU - Heeren, Pieter
AU - Puts, Martine
AU - Topinkova, Eva
AU - Janssen-Heijnen, Maryska L. G.
AU - Extermann, Martine
AU - Falandry, Claire
AU - Artz, Andrew
AU - Brain, Etienne
AU - Colloca, Giuseppe
AU - Flamaing, Johan
AU - Karnakis, Theodora
AU - Kenis, Cindy
AU - Audisio, Riccardo A.
AU - Mohile, Supriya
AU - Repetto, Lazzaro
AU - Van Leeuwen, Barbara
AU - Milisen, Koen
AU - Hurria, Arti
PY - 2014/8/20
Y1 - 2014/8/20
N2 - Purpose To update the International Society of Geriatric Oncology (SIOG) 2005 recommendations on geriatric assessment (GA) in older patients with cancer. Methods SIOG composed a panel with expertise in geriatric oncology to develop consensus statements after literature review of key evidence on the following topics: rationale for performing GA; findings from a GA performed in geriatric oncology patients; ability of GA to predict oncology treatment-related complications; association between GA findings and overall survival (OS); impact of GA findings on oncology treatment decisions; composition of a GA, including domains and tools; and methods for implementing GA in clinical care. Results GA can be valuable in oncology practice for following reasons: detection of impairment not identified in routine history or physical examination, ability to predict severe treatment-related toxicity, ability to predict OS in a variety of tumors and treatment settings, and ability to influence treatment choice and intensity. The panel recommended that the following domains be evaluated in a GA: functional status, comorbidity, cognition, mental health status, fatigue, social status and support, nutrition, and presence of geriatric syndromes. Although several combinations of tools and various models are available for implementation of GA in oncology practice, the expert panel could not endorse one over another. Conclusion There is mounting data regarding the utility of GA in oncology practice; however, additional research is needed to continue to strengthen the evidence base.
AB - Purpose To update the International Society of Geriatric Oncology (SIOG) 2005 recommendations on geriatric assessment (GA) in older patients with cancer. Methods SIOG composed a panel with expertise in geriatric oncology to develop consensus statements after literature review of key evidence on the following topics: rationale for performing GA; findings from a GA performed in geriatric oncology patients; ability of GA to predict oncology treatment-related complications; association between GA findings and overall survival (OS); impact of GA findings on oncology treatment decisions; composition of a GA, including domains and tools; and methods for implementing GA in clinical care. Results GA can be valuable in oncology practice for following reasons: detection of impairment not identified in routine history or physical examination, ability to predict severe treatment-related toxicity, ability to predict OS in a variety of tumors and treatment settings, and ability to influence treatment choice and intensity. The panel recommended that the following domains be evaluated in a GA: functional status, comorbidity, cognition, mental health status, fatigue, social status and support, nutrition, and presence of geriatric syndromes. Although several combinations of tools and various models are available for implementation of GA in oncology practice, the expert panel could not endorse one over another. Conclusion There is mounting data regarding the utility of GA in oncology practice; however, additional research is needed to continue to strengthen the evidence base.
U2 - 10.1200/JCO.2013.54.8347
DO - 10.1200/JCO.2013.54.8347
M3 - Article
C2 - 25071125
SN - 0732-183X
VL - 32
SP - 2595
EP - 2603
JO - Journal of Clinical Oncology
JF - Journal of Clinical Oncology
IS - 24
ER -