Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice

Lise Gutknecht, Sandy Popp, Jonas Waider, Frank M. J. Sommerlandt, Corinna Goeppner, Antonia Post, Andreas Reif, Daniel van den Hove, Tatyana Strekalova, Angelika Schmitt, Maria B. N. Colaco, Claudia Sommer, Rupert Palme, Klaus-Peter Lesch

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)2429-2441
JournalPsychopharmacology
Volume232
Issue number14
DOIs
Publication statusPublished - Jul 2015

Keywords

  • Serotonin
  • Tryptophan hydroxylase-2 (Tph2)
  • Chronic stress
  • Gene-by-environment interaction
  • Anxiety
  • Fear
  • Depression
  • Aggression

Cite this

Gutknecht, L., Popp, S., Waider, J., Sommerlandt, F. M. J., Goeppner, C., Post, A., Reif, A., van den Hove, D., Strekalova, T., Schmitt, A., Colaco, M. B. N., Sommer, C., Palme, R., & Lesch, K-P. (2015). Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice. Psychopharmacology, 232(14), 2429-2441. https://doi.org/10.1007/s00213-015-3879-0