Interaction between plasma homocysteine and the MTHFR c.677C > T polymorphism is associated with site-specific changes in DNA methylation in humans

Alexander J Nash, Pooja R Mandaviya, Marie-Joe Dib, André G Uitterlinden, Joyce van Meurs, Sandra G Heil, Toby Andrew, Kourosh R Ahmadi*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Web of Science)
Original languageEnglish
Pages (from-to)833-843
Number of pages11
JournalFaseb Journal
Volume33
Issue number1
DOIs
Publication statusPublished - Jan 2019

Keywords

  • 1-carbon metabolism
  • DEMENTIA
  • DETERMINANTS
  • EXPRESSION
  • FOLATE INTAKE
  • HYPERHOMOCYSTEINEMIA
  • HYPOMETHYLATION
  • METABOLISM
  • METHYLENETETRAHYDROFOLATE-REDUCTASE
  • NEPHROPATHY
  • RISK-FACTOR
  • epigenetics
  • methylenetetrahydrofolate reductase
  • methylome-wide association study
  • vascular disease

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