Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective

Keyphrases

• Toxicogenomics 100%
• Interlaboratory 100%
• Chemical Carcinogenicity 100%
• Interlaboratory Reproducibility 100%
• Bioinformatics Perspective 100%
• Reclassification 50%
• Anonymized 50%
• Transcriptome 50%
• Gene Response 50%
• Analysis Protocol 50%
• Overall Assessment 50%
• Kidney 50%
• Microarray 50%
• Carcinogenicity 50%
• In Vitro System 50%
• Training Set 50%
• Carcinogenic Potential 50%
• Liver 50%
• Genome-wide Expression 50%
• Human Telomerase Reverse Transcriptase (hTERT) 50%
• Cellular Systems 50%
• Bioinformatics Workflow 50%
• In Vitro Assay 50%
• Hepatoblastoma 50%
• Interlaboratory Comparison 50%
• In Vitro Alternative to Animal Testing 50%
• Human-based 50%
• Renal Tubular Epithelial Cells 50%
• Unknown Compound 50%
• Gene Expression Measurements 50%
• Target Organ 50%
• Carcinogenic Hazards 50%

INIS

• humans 100%
• in vitro 100%
• interlaboratory comparisons 100%
• testing 80%
• assessments 60%
• genes 60%
• laboratories 40%
• kidneys 40%
• hazards 40%
• data analysis 40%
• carcinogens 40%
• liver 20%
• validation 20%
• animals 20%
• toxicity 20%
• organs 20%
• classification 20%
• prediction 20%
• readout systems 20%
• hepatomas 20%
• tubules 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Carcinogenicity 100%
• Toxicogenomics 100%
• Liver Cell Carcinoma 33%
• Animal Testing 33%
• Transcriptome 33%
• Toxicity Class 33%