Intention and preference to use long-acting injectable PrEP among MSM in the Netherlands: a diffusion of innovation approach

Haoyi Wang*, Hanne M.L. Zimmermann, David van de Vijver, Kai J. Jonas

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) is efficacious in preventing HIV among men-who-have-sex-with-men (MSM) and will be soon available in Europe. This study investigated the intention and preference to use LAI-PrEP among MSM in the Netherlands by employing a diffusion of innovation approach. This study had a cross-sectional design nested within a cohort study established in 2017 to understand oral PrEP use among MSM. 309 MSM completed the survey on their awareness, interest, intention, and preference for LAI-PrEP in June 2022. Among them, 83% showed high/very-high interest in, and 63% showed high/very-high intention to use LAI-PrEP. A repeated innovator effect from the early adopters to LAI-PrEP was not observed. Early adopters did not show increased intention to use LAI-PrEP compared to other MSM subgroups, but neither did PrEP-naïve nor PrEP-discontinued MSM. However, among the 218 current oral PrEP users, suboptimal adherence was associated with preference for LAI-PrEP but not with intention to use it. In conclusion, our findings indicated that an effective, available, and affordable LAI-PrEP would be welcomed in the Netherlands, but that its introduction may not significantly expand PrEP coverage. However, the introduction of LAI-PrEP in the Netherlands could prove beneficial to MSM with suboptimal adherence to oral PrEP.
Original languageEnglish
Pages (from-to)89-100
Number of pages12
JournalAids Care-Psychological and Socio-Medical Aspects of Aids/Hiv
Volume36
Issue numbersup1
Early online date7 May 2024
DOIs
Publication statusPublished - 2024

Keywords

  • diffusion of innovation
  • intention and preference
  • long-acting injectable PrEP
  • Men who have sex with men
  • suboptimal PrEP adherence

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