Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity

Wim F. P. M. Van den Hof; Anke Van Summeren; Arjen Lommen; Maarten L. J. Coonen; Karen Brauers; Marcel van Herwijnen; Will K. W. H. Wodzig; Jos C. S. Kleinjans

doi:10.1016/j.tox.2014.06.003

Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity

Wim F. P. M. Van den Hof, Anke Van Summeren, Arjen Lommen, Maarten L. J. Coonen, Karen Brauers, Marcel van Herwijnen, Will K. W. H. Wodzig, Jos C. S. Kleinjans

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	18-26
Journal	Toxicology
Volume	324
DOIs	https://doi.org/10.1016/j.tox.2014.06.003
Publication status	Published - 3 Oct 2014

Keywords

Cyclosporin A
Primary mouse hepatocytes
Integrated analysis
Cholestasis
Hepatotoxicity

Access to Document

10.1016/j.tox.2014.06.003

Cite this

@article{3cc670d1da8d4ebbb44da086ee1e313d,

title = "Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity",

keywords = "Cyclosporin A, Primary mouse hepatocytes, Integrated analysis, Cholestasis, Hepatotoxicity",

author = "{Van den Hof}, {Wim F. P. M.} and {Van Summeren}, Anke and Arjen Lommen and Coonen, {Maarten L. J.} and Karen Brauers and {van Herwijnen}, Marcel and Wodzig, {Will K. W. H.} and Kleinjans, {Jos C. S.}",

year = "2014",

month = oct,

day = "3",

doi = "10.1016/j.tox.2014.06.003",

language = "English",

volume = "324",

pages = "18--26",

journal = "Toxicology",

issn = "0300-483X",

publisher = "Elsevier Ireland Ltd",

}

Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity. / Van den Hof, Wim F. P. M.; Van Summeren, Anke; Lommen, Arjen; Coonen, Maarten L. J.; Brauers, Karen; van Herwijnen, Marcel ; Wodzig, Will K. W. H.; Kleinjans, Jos C. S.

In: Toxicology, Vol. 324, 03.10.2014, p. 18-26.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity

AU - Van den Hof, Wim F. P. M.

AU - Van Summeren, Anke

AU - Lommen, Arjen

AU - Coonen, Maarten L. J.

AU - Brauers, Karen

AU - van Herwijnen, Marcel

AU - Wodzig, Will K. W. H.

AU - Kleinjans, Jos C. S.

PY - 2014/10/3

Y1 - 2014/10/3

KW - Cyclosporin A

KW - Primary mouse hepatocytes

KW - Integrated analysis

KW - Cholestasis

KW - Hepatotoxicity

U2 - 10.1016/j.tox.2014.06.003

DO - 10.1016/j.tox.2014.06.003

M3 - Article

C2 - 25047351

VL - 324

SP - 18

EP - 26

JO - Toxicology

JF - Toxicology

SN - 0300-483X

ER -