Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity

Wim F. P. M. Van den Hof; Anke Van Summeren; Arjen Lommen; Maarten L. J. Coonen; Karen Brauers; Marcel van Herwijnen; Will K. W. H. Wodzig; Jos C. S. Kleinjans

doi:10.1016/j.tox.2014.06.003

Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity

Wim F. P. M. Van den Hof^*, Anke Van Summeren, Arjen Lommen, Maarten L. J. Coonen, Karen Brauers, Marcel van Herwijnen, Will K. W. H. Wodzig, Jos C. S. Kleinjans

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

18 Citations (Web of Science)

Original language	English
Pages (from-to)	18-26
Journal	Toxicology
Volume	324
DOIs	https://doi.org/10.1016/j.tox.2014.06.003
Publication status	Published - 3 Oct 2014

Keywords

Cyclosporin A
Primary mouse hepatocytes
Integrated analysis
Cholestasis
Hepatotoxicity

Access to Document

10.1016/j.tox.2014.06.003

Cite this

@article{3cc670d1da8d4ebbb44da086ee1e313d,

title = "Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity",

keywords = "Cyclosporin A, Primary mouse hepatocytes, Integrated analysis, Cholestasis, Hepatotoxicity",

author = "{Van den Hof}, {Wim F. P. M.} and {Van Summeren}, Anke and Arjen Lommen and Coonen, {Maarten L. J.} and Karen Brauers and {van Herwijnen}, Marcel and Wodzig, {Will K. W. H.} and Kleinjans, {Jos C. S.}",

year = "2014",

month = oct,

day = "3",

doi = "10.1016/j.tox.2014.06.003",

language = "English",

volume = "324",

pages = "18--26",

journal = "Toxicology",

issn = "0300-483X",

publisher = "Elsevier Ireland Ltd",

}

Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity. / Van den Hof, Wim F. P. M.; Van Summeren, Anke; Lommen, Arjen; Coonen, Maarten L. J.; Brauers, Karen; van Herwijnen, Marcel ; Wodzig, Will K. W. H.; Kleinjans, Jos C. S.

In: Toxicology, Vol. 324, 03.10.2014, p. 18-26.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity

AU - Van den Hof, Wim F. P. M.

AU - Van Summeren, Anke

AU - Lommen, Arjen

AU - Coonen, Maarten L. J.

AU - Brauers, Karen

AU - van Herwijnen, Marcel

AU - Wodzig, Will K. W. H.

AU - Kleinjans, Jos C. S.

PY - 2014/10/3

Y1 - 2014/10/3

KW - Cyclosporin A

KW - Primary mouse hepatocytes

KW - Integrated analysis

KW - Cholestasis

KW - Hepatotoxicity

U2 - 10.1016/j.tox.2014.06.003

DO - 10.1016/j.tox.2014.06.003

M3 - Article

C2 - 25047351

VL - 324

SP - 18

EP - 26

JO - Toxicology

JF - Toxicology

SN - 0300-483X

ER -