Insulin receptor in the brain: Mechanisms of activation and the role in the CNS pathology and treatment

Igor Pomytkin, Joao P. Costa-Nunes, Vladimir Kasatkin, Ekaterina Veniaminova, Anna Demchenko, Alexey Lyundup, Klaus-Peter Lesch, Eugene D. Ponomarev, Tatyana Strekalova

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Pages (from-to)763-774
Number of pages12
JournalCNS Neuroscience & Therapeutics
Volume24
Issue number9
DOIs
Publication statusPublished - 1 Sep 2018

Keywords

  • Alzheimer's disease
  • central nervous system
  • insulin receptor
  • insulin receptor sensitizers
  • insulin-like growth factor-2
  • mitochondria
  • GROWTH-FACTOR-II
  • CENTRAL-NERVOUS-SYSTEM
  • MILD COGNITIVE IMPAIRMENT
  • PILOT-CLINICAL-TRIAL
  • OXYGEN-GLUCOSE DEPRIVATION
  • ALZHEIMERS-DISEASE
  • INTRANASAL INSULIN
  • HYDROGEN-PEROXIDE
  • GENE-EXPRESSION
  • IN-VIVO

Cite this

Pomytkin, I., Costa-Nunes, J. P., Kasatkin, V., Veniaminova, E., Demchenko, A., Lyundup, A., Lesch, K-P., Ponomarev, E. D., & Strekalova, T. (2018). Insulin receptor in the brain: Mechanisms of activation and the role in the CNS pathology and treatment. CNS Neuroscience & Therapeutics, 24(9), 763-774. https://doi.org/10.1111/cns.12866