Insights in the autoimmunity of myasthenia gravis

Marc H. De Baets*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Web of Science)

Abstract

Myasthenia gravis is a prototype anti-receptor autoimmune disease. Antibodies against proteins at the neuromuscular junction cause a defect in the signal transmission from nerve terminal to the damaged postsynaptic membrane. This issue of Autoimmunity reviews the mechanisms that lead to the destruction of the neuromuscular junction and the role of the thymus in myasthenia gravis and its animal models. In addition, this issue explores recent advances in diagnosis and treatment of this disease.
Original languageEnglish
Pages (from-to)341-343
JournalAutoimmunity
Volume43
Issue number5-6
DOIs
Publication statusPublished - 2010

Keywords

  • Myasthenia gravis
  • autoimmunity
  • acetylcholine receptor
  • muscle-specific tyrosine kinase
  • neuromuscular

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