Inhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice

Olga C. Jorge-Torres, Karolina Szczesna, Laura Roa, Carme Casal, Louisa Gonzalez-Somermeyer, Marta Soler, Cecilia D. Velasco, Pablo Martinez-San Segundo, Paolo Petazzi, Mauricio A. Saez, Raul Delgado-Morales, Stephane Fourcade, Aurora Pujol, Dori Huertas, Artur Llobet, Sonia Guil, Manel Esteller

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1665-1677
Number of pages13
JournalCell Reports
Volume23
Issue number6
DOIs
Publication statusPublished - 8 May 2018

Keywords

  • GLYCOGEN-SYNTHASE KINASE-3
  • LONG-TERM POTENTIATION
  • ALZHEIMERS-DISEASE
  • MOUSE MODEL
  • TYROSINE PHOSPHORYLATION
  • PROTEIN-SYNTHESIS
  • INACTIVATION
  • MECP2
  • GSK3-BETA
  • NEURONS

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