Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo

Yaw Asare, Miriam Ommer, Florence. A. Azombo, Setareh Alampour-Rajabi, Marieke Sternkopf, Maryam Sanati, Marion J. Gijbels, Corinna Schmitz, Dzmitry Sinitski, Pathricia V. Tilstam, Hongqi Lue, Andre Gessner, Denise Lange, Johannes A. Schmid, Christian Weber, Martin Dichgans, Joachim Jankowski, Ruggero Pardi, Menno P. J. de Winther, Heidi NoelsJuergen Bernhagen

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)E2766-E2775
Number of pages10
JournalProceedings of the National Academy of Sciences of the United States of America
Volume114
Issue number13
DOIs
Publication statusPublished - 14 Mar 2017

Keywords

  • COP9 signalosome
  • atherosclerosis
  • inflammation
  • NEDDylation
  • MLN4924
  • NF-KAPPA-B
  • NEDD8-ACTIVATING ENZYME-INHIBITOR
  • E-DEFICIENT MICE
  • ACUTE MYELOID-LEUKEMIA
  • MODULATE AP-1 ACTIVITY
  • EXPERIMENTAL ATHEROSCLEROSIS
  • ATTENUATES ATHEROSCLEROSIS
  • ENDOTHELIAL DYSFUNCTION
  • GENE-EXPRESSION
  • JAB1 INTERACTS

Cite this

Asare, Y., Ommer, M., Azombo, F. A., Alampour-Rajabi, S., Sternkopf, M., Sanati, M., Gijbels, M. J., Schmitz, C., Sinitski, D., Tilstam, P. V., Lue, H., Gessner, A., Lange, D., Schmid, J. A., Weber, C., Dichgans, M., Jankowski, J., Pardi, R., de Winther, M. P. J., ... Bernhagen, J. (2017). Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo. Proceedings of the National Academy of Sciences of the United States of America, 114(13), E2766-E2775. https://doi.org/10.1073/pnas.1618411114