Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague-Dawley Rats

Princy Khurana, Tulasi Yadati, Sandeep Goyal, Atul Dolas, Tom Houben, Yvonne Oligschlaeger, Anil K. Agarwal, Aditya Kulkarni, Ronit Shiri-Sverdlov*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number171
Number of pages12
JournalBiomolecules
Volume9
Issue number5
DOIs
Publication statusPublished - May 2019

Keywords

  • NAFLD
  • lysosomal enzyme
  • extracellular cathepsin D
  • small-molecule inhibitor
  • NONALCOHOLIC FATTY LIVER
  • INSULIN-RESISTANCE
  • ACCURATE DOCKING
  • PROCATHEPSIN-D
  • CHOLESTEROL
  • MODEL
  • METABOLISM
  • HYDROLASES
  • PROTEASES
  • PRODUCTS

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