Influence of paternal age on ongoing pregnancy rate at eight weeks' gestation in assisted reproduction

Aukje Marieke Meijerink*, Liliana Ramos, Kathrin Fleischer, Joris A. Veltman, Jan C. Hendriks, Didi D. Braat

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


A retrospective cohort study was performed with the followings aims: to evaluate the influence of paternal age on best embryo quality available for embryo transfer on the third day; biochemical pregnancy rate; miscarriage rate and ongoing pregnancy rate at 8 weeks' gestational age, after IVF or intracytoplasmic sperm injection (ICSI) treatment, respectively, including treatment with non-ejaculated spermatozoa. In total, 7051 first IVF/ICSI cycles in Radboud university medical center, between 1 January 2001 and 1 June 2013 were included in this study. A statistical model was used to analyse the effect of paternal age and maternal age. No statistically significant differences between the paternal age groups were found with respect to the probability of an ongoing pregnancy after the first cycle (35-44 years: odds ratio [OR] = 0.97 [95% confidence interval [CI]: 0.86 to 1.10] and ?45 years: OR = 1.01 [95% CI: 0.82 to 1.26]), respectively, compared with
Original languageEnglish
Pages (from-to)96-103
JournalReproductive Biomedicine Online
Issue number1
Publication statusPublished - Jan 2016


  • assisted reproductive techniques
  • male infertility
  • paternal age
  • pregnancy rate
  • semen
  • spermatozoa

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