Influence of muscarinic M-1 receptor antagonism on brain choline levels and functional connectivity in medication-free subjects with psychosis: A placebo controlled, cross-over study

Claudia Vingerhoets*, Geor Bakker, Anouk Schrantee, Marieke van der Pluijm, Oswald J. N. Bloemen, Liesbeth Reneman, Matthan Caan, Jan Booij, Therese A. M. J. van Amelsvoort

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)5-13
Number of pages9
JournalPsychiatry Research-Neuroimaging
Volume290
DOIs
Publication statusPublished - 30 Aug 2019

Keywords

  • H-1-MRS
  • Cognition
  • Psychosis
  • Choline
  • Muscarinic M-1 receptor
  • Biperiden
  • Resting-state fMRI
  • MAGNETIC-RESONANCE-SPECTROSCOPY
  • ANTIPSYCHOTIC-NAIVE PATIENTS
  • 1ST EPISODE
  • UNTREATED PSYCHOSIS
  • NICOTINIC RECEPTORS
  • PREFRONTAL CORTEX
  • SCHIZOPHRENIA
  • COGNITION
  • BINDING
  • BIPERIDEN

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