Influence of MMP inhibitor GM6001 loading of fibre coated polypropylene meshes on wound healing: Implications for hernia repair

Gabriele Boehm*, Juergen Groll, Karl-Heinz Heffels, Nicole Heussen, Peter Ink, Hamid Patrick Alizai, Ulf Peter Neumann, Reinhild Schnabel, Ursula Mirastschijski

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1343-1359
Number of pages17
JournalJournal of Biomaterials Applications
Volume32
Issue number10
DOIs
Publication statusPublished - May 2018

Keywords

  • Polypropylene mesh
  • GM6001
  • matrix metalloproteinase inhibitor
  • electrospinning
  • nanofibre
  • poly(lactic-co-glycolic acid)
  • sP(EO-stat-PO)
  • hernia repair
  • neovascularization
  • matrix metalloproteinase-2
  • matrix metalloproteinase-9
  • MATRIX-METALLOPROTEINASE INHIBITION
  • HUMAN-SKIN
  • MYOFIBROBLAST FORMATION
  • INFLAMMATORY RESPONSE
  • INGUINAL-HERNIA
  • GROWTH-FACTORS
  • GROIN HERNIA
  • COLLAGEN
  • IMPLANTATION
  • ENVIRONMENT

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