The aim of this study was to evaluate the effect of house dust mite impermeable covers on asthma-specific health-related quality of life in adult asthmatic patients that were trained in guided self-management. In a 2-year randomized placebo-controlled clinical trial, information on the quality of life was collected. The improvement of Mini Asthma Quality of Life Questionnaire (AQLQ) score in the allergens-avoidance group (0.26) was comparable to the improvement in the placebo group (0.30) and not significant. HDM-impermeable covers for pillows, duvets, and mattresses did not result in improved health-related quality of life.
van den Bemt, L., de Vries, M. P., Cloosterman, S. G. M., Thoonen, B. P. A., Muris, J. W. M., Goossens, M. E. J. B., Wesseling, G. J., & van Schayck, C. P. (2007). Influence of house dust mite impermeable covers on health-related quality of life of adult patients with asthma: results of a randomized clinical trial. Journal of Asthma, 44(10), 843-848. https://doi.org/10.1080/02770900701752318