TY - JOUR
T1 - Inflation and Bi-Axial Tensile Testing of Healthy Porcine Carotid Arteries
AU - Boekhoven, Renate W.
AU - Peters, Mathijs F. J.
AU - Rutten, Marcel C. M.
AU - van Sambeek, Marc R.
AU - van de Vosse, Frans N.
AU - Lopata, Richard
PY - 2016/2
Y1 - 2016/2
N2 - Knowledge of the intrinsic material properties of healthy and diseased arterial tissue components is of?great importance in diagnostics. This study describes an in?vitro comparison of 13 porcine carotid arteries using?inflation testing combined with functional ultrasound and bi-axial tensile testing. The measured tissue behavior was described using both a linear, but geometrically non-linear, one-parameter (neo-Hookean) model and a two-parameter non-linear (Demiray) model. The shear modulus estimated using the linear model resulted in?good agreement between the ultrasound and tensile testing methods, GUS?=?25?5.7?kPa and GTT?=?23?5.4?kPa. No significant correspondence was observed for the non-linear model aUS?=?1.0?2.7?kPa vs. aTT?=?17?8.8?kPa, p? 0); however, the exponential parameters were in correspondence (bUS?=?12?4.2 vs. bTT?=?10?1.7, p > 0.05). Estimation of more complex models in?vivo is cumbersome considering the sensitivity of the model parameters to small changes in measurement data and the absence of intraluminal pressure data, endorsing the use of a simple, linear model in?vivo. World Federation for Ultrasound in Medicine & Biology.
AB - Knowledge of the intrinsic material properties of healthy and diseased arterial tissue components is of?great importance in diagnostics. This study describes an in?vitro comparison of 13 porcine carotid arteries using?inflation testing combined with functional ultrasound and bi-axial tensile testing. The measured tissue behavior was described using both a linear, but geometrically non-linear, one-parameter (neo-Hookean) model and a two-parameter non-linear (Demiray) model. The shear modulus estimated using the linear model resulted in?good agreement between the ultrasound and tensile testing methods, GUS?=?25?5.7?kPa and GTT?=?23?5.4?kPa. No significant correspondence was observed for the non-linear model aUS?=?1.0?2.7?kPa vs. aTT?=?17?8.8?kPa, p? 0); however, the exponential parameters were in correspondence (bUS?=?12?4.2 vs. bTT?=?10?1.7, p > 0.05). Estimation of more complex models in?vivo is cumbersome considering the sensitivity of the model parameters to small changes in measurement data and the absence of intraluminal pressure data, endorsing the use of a simple, linear model in?vivo. World Federation for Ultrasound in Medicine & Biology.
KW - Ultrasound elastography
KW - Carotid artery
KW - Inflation testing
KW - Bi-axial tensile testing
U2 - 10.1016/j.ultrasmedbio.2015.09.019
DO - 10.1016/j.ultrasmedbio.2015.09.019
M3 - Article
C2 - 26598396
SN - 0301-5629
VL - 42
SP - 574
EP - 585
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 2
ER -